Results 21 to 30 of about 3,707 (163)
BMC Musculoskeletal Disorders, 2021 Background The enthesis possesses morphological adaptations across the soft-hard tissue junction which are not fully restored during surgical avulsion repairs.
Jeremy W. Mortimer +4 more
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eLife, 2023 The attachment site of the rotator cuff (RC) is a classic fibrocartilaginous enthesis, which is the junction between bone and tendon with typical characteristics of a fibrocartilage transition zone. Enthesis development has historically been studied with
Tao Zhang +5 more
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Journal of Bone and Joint Surgery, 2018 Abstract: On May 22, 2017, the National Institutes of Health (NIH)/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) hosted a roundtable on “Innovative Treatments for Enthesis Repair.” A summary of the roundtable discussion, as well as a list of the extramural participants, can be found at https://www.niams.nih.gov/
Kathleen A. Derwin +3 more
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Enthesis Healing Is Dependent on Scaffold Interphase Morphology—Results from a Rodent Patellar Model
Cells, 2022 The use of multiphasic scaffolds to treat injured tendon-to-bone entheses has shown promising results in vitro. Here, we used two versions of a biphasic silk fibroin scaffold to treat an enthesis defect created in a rat patellar model in vivo.
Carlos J. Peniche Silva +10 more
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Frontiers in Bioengineering and Biotechnology, 2021 The musculoskeletal system is composed by hard and soft tissue. These tissues are characterized by a wide range of mechanical properties that cause a progressive transition from one to the other.
Alberto Sensini +6 more
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eLife, 2021 The mechanical challenge of attaching elastic tendons to stiff bones is solved by the formation of a unique transitional tissue. Here, we show that murine tendon-to-bone attachment cells are bi-fated, activating a mixture of chondrocyte and tenocyte ...
Shiri Kult +15 more
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Cells, 2021 Objective: The spondylarthritides (SpA) are intimately linked to new bone formation and IL-17A and TNF pathways. We investigated spinal soft tissue and bone mesenchymal stem cell (MSC) responses to IL-17A and TNF, including their osteogenesis ...
Tobias Russell +12 more
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Tendon enthesis positional recruitment model
, 2021 A mathematical model was developed to describe the mechanics of the tendon enthesis across a range of joint orientations and geometries. This zip file contains all relevant code for the simulations in this paper. The MATLAB codes are as follow: 1) WORKING_V5_Postural_RecruitmentModel.m — runs the positional recruitment model with specified parameters 2)
Golman, Michael +2 more
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Scientific Reports, 2021 The enthesis allows the insertion of tendon into bone thanks to several remarkable strategies. This complex and clinically relevant location often features a thin layer of fibrocartilage sandwiched between tendon and bone to cope with a highly ...
Alexandra Tits +8 more
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Bone & Joint Research, 2023 Aims: It has been established that mechanical stimulation benefits tendon-bone (T-B) healing, and macrophage phenotype can be regulated by mechanical cues; moreover, the interaction between macrophages and mesenchymal stem cells (MSCs) plays a ...
Linfeng Wang +7 more
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