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Entorhinal cortex and cognition
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2009Understanding the function of the entorhinal cortex (EC) has been an important subject over the years, not least because of its cortical intermediary to and from the hippocampus proper, and because of electrophysiological advances which have started to reveal the physiology in behaving animals.
Etienne, Coutureau, Georges, Di Scala
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Computational Modeling of Entorhinal Cortex
Annals of the New York Academy of Sciences, 2000Computational modeling provides a means for linking the physiological and anatomical characteristics of entorhinal cortex at a cellular level to the functional role of this region in behavior. We have developed detailed simulations of entorhinal cortical neurons and networks, with an emphasis on the role of acetylcholine in entorhinal cortical function.
M E, Hasselmo +3 more
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2010
While decades of study have unraveled some of the basic principles of hippocampal structure and function, the adjacent entorhinal cortex (EC) has remained terra incognita in many respects. Recent studies suggest that the medial part of the entorhinal cortex is part of a two-dimensional metric map of the animal’s changing location in the environment.
Edvard I. Moser +2 more
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While decades of study have unraveled some of the basic principles of hippocampal structure and function, the adjacent entorhinal cortex (EC) has remained terra incognita in many respects. Recent studies suggest that the medial part of the entorhinal cortex is part of a two-dimensional metric map of the animal’s changing location in the environment.
Edvard I. Moser +2 more
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Speed cells in the medial entorhinal cortex
Grid cells in the medial entorhinal cortex have spatial firing fields that repeat periodically in a hexagonal pattern. When animals move, activity is translated between grid cells in accordance with the animal's displacement in the environment. For this translation to occur, grid cells must have continuous access to information about instantaneous ...
James E Carmichael +2 more
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Decreased entorhinal cortex volumes in schizophrenia
Schizophrenia Research, 2008The entorhinal cortex is located in the medial temporal lobe and is involved in memory and learning. Previous MRI studies reported conflicting findings in schizophrenia, showing normal or reduced entorhinal size.To explore entorhinal cortex volumes in a large sample of patients with schizophrenia recruited from the geographically defined catchment area
Baiano M +11 more
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Spatial Representation in the Entorhinal Cortex
Science, 2004As the interface between hippocampus and neocortex, the entorhinal cortex is likely to play a pivotal role in memory. To determine how information is represented in this area, we measured spatial modulation of neural activity in layers of medial entorhinal cortex projecting to the hippocampus.
Marianne, Fyhn +4 more
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Entorhinal cortex pathology in Alzheimer's disease
Hippocampus, 1991AbstractThe anatomical distribution of pathological changes in Alzheimer's disease, although highly selective for only certain brain areas, can be widespread at the endstage of the illness and can affect many neural systems. Propriety for onset among these is a question of importance for clues to the etiology of the disease, but one that is formidable ...
G W, Van Hoesen +2 more
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Hippocampus, 1995
AbstractThe pattern of impulse transfer along the entorhinal‐hippocampal‐entorhinal loop has been analyzed in the guinea pig by field potential analysis. The loop was driven by impulse volleys conducted by presubicular commissural fibers, directly stimulated in the dorsal psalterium, which monosynaptically activated perforant path neurons in the medial
Bartesaghi, R, Gessi, T, Migliore, M
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AbstractThe pattern of impulse transfer along the entorhinal‐hippocampal‐entorhinal loop has been analyzed in the guinea pig by field potential analysis. The loop was driven by impulse volleys conducted by presubicular commissural fibers, directly stimulated in the dorsal psalterium, which monosynaptically activated perforant path neurons in the medial
Bartesaghi, R, Gessi, T, Migliore, M
openaire +4 more sources

