Results 51 to 60 of about 41,716 (223)

Epileptic arousals: A neglected clinical entity

Epilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel, Nóra Pető, Sotirios Kalousios, Nicolas Zabler, Armin Brandt, Peter C. Reinacher, Dieter Riemann, Mohammad F. Khazali, Andreas Schulze‐Bonhage   +8 more
wiley   +1 more source

Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid

Communications Medicine, 2023
Introduction Non-invasive diffusion-weighted imaging (DWI) to assess brain microstructural changes via cortical mean diffusivity (cMD) has been shown to be cross-sectionally associated with tau in cognitively normal older adults, suggesting that it might
Geoffroy Gagliardi, Elena Rodriguez-Vieitez, Victor Montal, Jorge Sepulcre, Ibai Diez, Cristina Lois, Bernard Hanseeuw, Aaron P. Schultz, Michael J. Properzi, Kathryn V. Papp, Gad A. Marshall, Juan Fortea, Keith A. Johnson, Reisa A. Sperling, Patrizia Vannini   +14 more
doaj   +1 more source

Brain‐wide magnetic resonance imaging analysis of neurobehavioral comorbidities in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), patients often present with neurobehavioral comorbidities encompassing affective and cognitive difficulties. Whereas the latter have been related to atypical connectivity of mesiotemporal and frontotemporal circuits, the brain basis of affective symptoms remains incompletely understood.
Fatemeh Fadaie, Benoit Caldairou, Boris C. Bernhardt, Andrea Bernasconi, Neda Bernasconi   +4 more
wiley   +1 more source

Involvement of the hippocampus, amygdala, entorhinal cortex and posterior parietal cortex in memory consolidation

Brazilian Journal of Medical and Biological Research, 1997
A total of 182 young adult male Wistar rats were bilaterally implanted with cannulae into the CA1 region of the dorsal hippocampus and into the amygdaloid nucleus, the entorhinal cortex, and the posterior parietal cortex. After recovery, the animals were
M.S. Zanatta, J.H. Quillfeldt, E. Schaeffer, P.K. Schmitz, J. Quevedo, J.H. Medina, I. Izquierdo   +6 more
doaj   +1 more source

Speed cells in the medial entorhinal cortex

Nature, 2015
Grid cells in the medial entorhinal cortex have spatial firing fields that repeat periodically in a hexagonal pattern. When animals move, activity is translated between grid cells in accordance with the animal's displacement in the environment. For this translation to occur, grid cells must have continuous access to information about instantaneous ...
Emilio Kropff, James E. Carmichael, May-Britt Moser, Edvard I. Moser   +3 more
openaire   +3 more sources

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

Nature Communications, 2016
Whether Alzheimer’s disease originates in basal forebrain or entorhinal cortex remains highly debated. Here the authors use structural magnetic resonance data from a longitudinal sample of participants stratified by cerebrospinal biomarker and clinical ...
Taylor W. Schmitz, R. Nathan Spreng, The Alzheimer's Disease Neuroimaging Initiative   +2 more
doaj   +1 more source

Two Alzheimer’s disease risk genes increase entorhinal cortex volume in young adults

Frontiers in Human Neuroscience, 2014
Alzheimer’s disease (AD) risk genes alter brain structure and function decades before disease onset. Apolipoprotein E (APOE) is the strongest known genetic risk factor for Alzheimer’s disease, and a related gene, apolipoprotein J (APOJ), also affects ...
Amanda Marie Dibattista, Benson W Stevens, Benson W Stevens, G William Rebeck, Adam E. Green   +4 more
doaj   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Predictive grid cells: Future spatial representations in the hippocampal-entorhinal circuit

Neuroscience Research
Place cells in the hippocampus and grid cells in the entorhinal cortex have long been interpreted as neural representations of an animal’s current location in space. However, an increasing amount of theoretical and experimental evidence suggests that the
Ayako Ouchi
doaj   +1 more source