Results 71 to 80 of about 72,632 (202)

CA1-projecting subiculum neurons facilitate object-place learning. [PDF]

, 2019
Recent anatomical evidence suggests a functionally significant back-projection pathway from the subiculum to the CA1. Here we show that the afferent circuitry of CA1-projecting subicular neurons is biased by inputs from CA1 inhibitory neurons and the ...
Chen, Lujia, Golshani, Peyman, Holmes, Todd C, Jiang, Li, Jin, Suoqin, Johnston, Kevin G, Lin, Xiaoxiao, Nie, Qing, Nitz, Douglas A, Qiao, Xin, Sun, Yanjun, Xu, Xiangmin, Zhou, Pengcheng   +12 more
core   +1 more source

A mouse model of early sporadic tau pathology induces neurogenic plasticity in the hippocampus.

PLoS ONE
Alzheimer's disease varies by sex but is broadly characterized by widespread neurodegeneration and the accumulation of insoluble amyloid plaques and neurofibrillary tangles.
Alyssa M Ash, Sue Rim Baek, Peyton Holder, Sara Singh, Nicholas P Vyleta, Matthew Willman, Kevin R Nash, Jason S Snyder   +7 more
doaj   +1 more source

Convergent Projections from Perirhinal and Postrhinal Cortices Suggest a Multisensory Nature of Lateral, but Not Medial, Entorhinal Cortex

Cell Reports, 2019
Summary: The current model of the organization of the medial temporal lobe (MTL) episodic memory system assumes that two functionally different “where” and “what” pathways enter MTL as parallel parahippocampal cortex (PHC)-medial entorhinal cortex (MEC ...
Thanh P. Doan, Maria J. Lagartos-Donate, Eirik S. Nilssen, Shinya Ohara, Menno P. Witter   +4 more
doaj   +1 more source

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira, Buée, Luc, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles R., Hof, Patrick R., Jovanov-Milošević, Nataša, Leko, Mirjana Babić, Silva, Rohan de, Wischik, Claude M., Wray, Selina, Šimić, Goran   +11 more
core   +1 more source

CORRELATION BETWEEN MRI-BASED BRAIN VOLUME CHANGES AND COGNITIVE DECLINE IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT: A PROSPECTIVE OBSERVATIONAL STUDY.

Student's Journal of Health Research Africa
Background Mild Cognitive Impairment (MCI) is an intermediate stage between normal cognitive aging and dementia, characterized by subtle cognitive decline.
Karishma Khushalrao Surpam
doaj   +1 more source

Combinatorial expression of Lef1, Lhx2, Lhx5, Lhx9, Lmo3, Lmo4, and Prox1 helps to identify comparable subdivisions in the developing hippocampal formation of mouse and chicken

Frontiers in Neuroanatomy, 2014
We carried out a study of the expression patterns of seven developmental regulatory genes (Lef1, Lhx2, Lhx9, Lhx5, Lmo3, Lmo4, and Prox1), in combination with topological position, to identify the medial pallial derivatives, define its major subdivisions,
Antonio eAbellán, Ester eDesfilis, Loreta eMedina   +2 more
doaj   +1 more source

Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression [PDF]

, 2009
The release of inflammatory mediators following cortical spreading depression (CSD) is suggested to play a role in pathophysiology of CSD-related neurological disorders.
Aghabarari, A., Ghaemi, A., Gorji, A., Khaleghi Ghadiri, M., Khodaie, B., Lotfinia, A.A., Lotfinia, M., Meuth, S., Sajadian, A.   +8 more
core   +2 more sources

Differential role of entorhinal and hippocampal nerve growth factor in short- and long-term memory modulation

Brazilian Journal of Medical and Biological Research, 2005
We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention.
Walz R., Roesler R., Reinke A., Martins M.R., Quevedo J., Izquierdo I.   +5 more
doaj  

Postsynaptic Signals Mediating Induction of Long-Term Synaptic Depression in the Entorhinal Cortex

Neural Plasticity, 2008
The entorhinal cortex receives a large projection from the piriform cortex, and synaptic plasticity in this pathway may affect olfactory processing. In vitro whole cell recordings have been used here to investigate postsynaptic signalling mechanisms that
Saïd Kourrich, Stephen D. Glasgow, Douglas A. Caruana, C. Andrew Chapman   +3 more
doaj   +1 more source

Structural development and dorsoventral maturation of the medial entorhinal cortex

eLife, 2016
We investigated the structural development of superficial-layers of medial entorhinal cortex and parasubiculum in rats. The grid-layout and cholinergic-innervation of calbindin-positive pyramidal-cells in layer-2 emerged around birth while reelin ...
Saikat Ray, Michael Brecht
doaj   +1 more source