Results 81 to 90 of about 72,560 (254)
Rationale for tau aggregation inhibitor therapy in Alzheimer's disease and other tauopathies [PDF]
, 2010 Preprin
Harrington, Charles R +3 more
core +1 more source
The human entorhinal cortex: A cytoarchitectonic analysis
Journal of Comparative Neurology, 1995 AbstractThe entorhinal cortex of man is in the medial aspect of the temporal lobe. As in other mammalian species, it constitutes an essential component of the hippocampal formation and the route through which the neocortex interacts with the hippocampus.
R, Insausti +4 more
openaire +2 more sources
Functional topography of the human entorhinal cortex [PDF]
eLife, 2015 Despite extensive research on the role of the rodent medial and lateral entorhinal cortex (MEC/LEC) in spatial navigation, memory and related disease, their human homologues remain elusive. Here, we combine high-field functional magnetic resonance imaging at 7 T with novel data-driven and model-based analyses to identify corresponding subregions in ...
Tobias Navarro Schröder +4 more
openaire +7 more sources
Animal Models and Experimental Medicine, EarlyView.Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee +3 more
wiley +1 more source
Two Alzheimer’s disease risk genes increase entorhinal cortex volume in young adults
Frontiers in Human Neuroscience, 2014 Alzheimer’s disease (AD) risk genes alter brain structure and function decades before disease onset. Apolipoprotein E (APOE) is the strongest known genetic risk factor for Alzheimer’s disease, and a related gene, apolipoprotein J (APOJ), also affects ...
Amanda Marie Dibattista +4 more
doaj +1 more source
Axonal regeneration in hippocampal and spinal cord organotypic slice cultures [PDF]
, 2010 Under normal conditions, axonal regeneration after lesions is not possible in mature CNS but can occur in embryonic and early postnatal nervous systems. In recent years, a number of possible strategies to enhance axonal regeneration and eventually treat ...
Bonnici, Brenda
core +1 more source
Entorhinal cortex stellate cell synchronization [PDF]
BMC Neuroscience, 2014 Theta-frequency oscillations (8-12 Hz) of large groups of synaptically coupled cells are commonly seen throughout the mammalian brain. The theta oscillations of entorhinal cortex grid cells and hippocampal place cells have received special attention recently due to their role they apparently play in the encoding of positional information. In a previous
Crotty, Patrick +3 more
openaire +1 more source
Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths
Annals of Neurology, EarlyView.Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian +10 more
wiley +1 more source
Neurobiology of Disease, 2008 We investigated the potential of 4-AP (50–100 μM) to induce seizure-like events (SLEs) in combined entorhinal cortex–hippocampal slices from Sprague Dawley rats which developed spontaneous limbic seizures following kainic acid induced status epilepticus.
Robert K. Zahn +5 more
doaj +1 more source
Scientific Reports, 2021 The regular equilateral triangular periodic firing pattern of grid cells in the entorhinal cortex is considered a regular metric for the spatial world, and the grid-like representation correlates with hexadirectional modulation of theta (4–8 Hz) power in
Wenjing Wang, Wenxu Wang
doaj +1 more source