Results 101 to 110 of about 312,386 (294)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Matching pre-equilibrium dynamics and viscous hydrodynamics

, 2010
We demonstrate how to match pre-equilibrium dynamics of a 0+1 dimensional quark gluon plasma to 2nd-order viscous hydrodynamical evolution. The matching allows us to specify the initial values of the energy density and shear tensor at the initial time of
Mauricio Martinez, Michael Strickland, S. R. de Groot   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Investigation to define the propagation characteristics of a finite amplitude acoustic pressure wave, phase 1 final report, 29 jun. 1964 - 29 jul. 1965 [PDF]

The contribution of high entropy production regions to the generation and propagation characteristics of a finite amplitude pressure is considered.
Li, T. C., Peter, A. C.
core   +1 more source

Statistical inference of the generation probability of T-cell receptors from sequence repertoires

, 2012
Stochastic rearrangement of germline DNA by VDJ recombination is at the origin of immune system diversity. This process is implemented via a series of stochastic molecular events involving gene choices and random nucleotide insertions between, and ...
A. M. Walczak, A. Murugan, Arstila, Blum, C. G. Callan, Cabaniols, Gauss, Lafaille, Lieber, Lieber, Mason, Monod, Robins, Schatz, T. Mora, Venturi, Verkaik, Wang, Weinstein   +18 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Computations of local nonsimilar solutions for MHD flow of Reiner–Rivlin fluid

Nonlinear Analysis
Here local nonsimilar solution for hydromagnetic stretched flow of Reiner–Rivlin material is constructed. Heat generation, radiation, and dissipation in thermal expression are studied.
Sohail A. Khan, Tasawar Hayat, Ahmed Alsaedi, Shaher Momani   +3 more
doaj   +1 more source

Entropy generation analysis for non-similar analytical study of nanofluid flow and heat transfer under the influence of aligned magnetic field

Alexandria Engineering Journal, 2018
The present semi-analytical investigation covers the impact of aligned magnetic field, Ohmic dissipation and viscous dissipation on a non-similar nanofluid flow over a plate with no flux condition.
Puneet Rana, Nisha Shukla
doaj   +1 more source

Entropy generation analysis for mixed convection flow of nanofluid due to vertical plate with chemical reaction effects. [PDF]

Sci Rep, 2023
Abdelhameed TN.
europepmc   +1 more source

Entropy generation analysis in greenhouse environmental system

Journal of Physics: Conference Series
Abstract To minimize energy loss in a greenhouse environmental system, analyzing the entropy generation within the system is crucial. Based on the established mathematical model of the greenhouse environment, entropy generation in the greenhouse environment system is analyzed, and the irreversible energy loss in the greenhouse ...
Shujiao Tian, Yixiao Chang, Riru Zhang, Zhijuan Zhang   +3 more
openaire   +1 more source