Results 111 to 120 of about 307,686 (282)

Mechanisms for Env Glycoprotein Acquisition by Retroviruses [PDF]

AIDS Research and Human Retroviruses, 2011
A mandatory step in the formation of an infectious retroviral particle is the acquisition of its envelope glycoprotein (Env). This step invariably occurs by Env positioning itself in the host membrane at the location of viral budding and being incorporated along with the host membrane into the viral particle.
openaire   +2 more sources

Twenty years of dynamic occupancy models: a review of applications and look to the future

Ecography, EarlyView.
Since their introduction over 20 years ago, dynamic occupancy models (DOMs) have become a powerful and flexible framework for estimating species occupancy across space and time while accounting for imperfect detection. As their popularity has increased and extensions have further expanded their capabilities, DOMs have been applied to increasingly ...
Saoirse Kelleher, Gurutzeta Guillera-Arroita, Jane Elith, Natalie J. Briscoe   +3 more
wiley   +1 more source

Successful Implementation of Environmental Policy and Governance: Understanding and Modeling Micro Governance

Environmental Policy and Governance, EarlyView.
ABSTRACT Successful implementation of environmental policy and governance highly depends on the capacity to know about, build new and utilize existing governance structures. However, the theoretical tools and available methods to assess the complexity of emerging or existing structures are rather limited.
Diana Giebels, Arend Ligtenberg, Martha Bakker   +2 more
wiley   +1 more source

Environmental evaluation of three alternative futures for organic dairy in Denmark. [PDF]

Objective of this study was to explore sustainability of scenarios for organic dairy farming based on visions and goals of the future, by parameterization at farm level.
Boer, I.J.M., de, Oudshoorn, F.W., Sorensen, C.A.G.   +2 more
core   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

On the Applicability of the Advocacy Coalition Framework for Analyzing EU Policy Processes

European Policy Analysis, EarlyView.
ABSTRACT Initially developed for the US context, the Advocacy Coalition Framework (ACF) is increasingly used to analyze policy processes in the EU. But policymaking in EU differs from the US context, why the applicability of ACF in the EU context should be scrutinized.
Fredrik von Malmborg
wiley   +1 more source

Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations.

PLoS Pathogens, 2018
HIV-1 envelope glycoprotein (Env) mediates virus attachment and entry into the host cells. Like other membrane-bound and secreted proteins, HIV-1 Env contains at its N terminus a signal peptide (SP) that directs the nascent Env to the endoplasmic ...
Chitra Upadhyay, Roya Feyznezhad, Weiming Yang, Hui Zhang, Susan Zolla-Pazner, Catarina E Hioe   +5 more
doaj   +1 more source

Perovskite‐based time‐domain signal‐balancing LiDAR sensor with centimeter depth resolution

InfoMat, EarlyView.
In this study, we present a monolithic high‐speed perovskite‐based photodetector capable of directly sensing the time delay between two light pulses with a temporal resolution of at least 170 ps. This outstanding time resolution is achieved through a signal‐balancing detection scheme that effectively overcomes the limitations of conventional ...
Gebhard J. Matt, Vitalii Bartosh, Joshua R. S. Lilly, Vincent J.‐Y. Lim, Lorenzo J. A. Ferraresi, Daria Proniakova, Yuliia Kominko, Gytis Juška, Laura M. Herz, Sergii Yakunin, Maksym V. Kovalenko   +10 more
wiley   +1 more source

Immunogenicity of HIV-1 Env mRNA and Env-Gag VLP mRNA Vaccines in Mice

Vaccines
Background: The development of a protective vaccine is critical for conclusively ending the human immunodeficiency virus (HIV) epidemic. Methods: We constructed nucleotide-modified mRNA vaccines expressing HIV-1 Env and Gag proteins.
Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Yanzhe Hao, Xia Feng   +5 more
doaj   +1 more source

CSR disclosure and investment efficiency in MENA countries: The moderating role of CSR committee

Strategic Change, EarlyView.
ABSTRACT Corporate social responsibility disclosure (CSRD) is often recognized as a transparency mechanism that allows companies to communicate their commitment to CSR. However, CSRD may also exacerbate agency conflicts. This study addresses these two contrasting perspectives by investigating the impact of CSRD on investment efficiency and exploring ...
Mohamed Malek Belhoula, Imen Khanchel, Naima Lassoued, Rouba Jebri   +3 more
wiley   +1 more source