Abstract Lys49 secreted phospholipase A2‐like proteins (sPLA2s) are major myotoxins in viperid snake venoms, causing rapid muscle damage in envenomation. Beyond their clinical relevance, these small non‐catalytic proteins provide a model to study how quaternary structure and conformational dynamics enable catalysis‐independent membrane disruption ...
Diane C. A. Lima +4 more
wiley +1 more source
<症例>マムシ (Agkistrodon halys Blomhoffii) 咬傷における少量抗毒素血清投与の経験 : 43症例の検討 [PDF]
Forty-three consecutive patients of venomous snakebite by the Japanese viper (Agkistrodon halys Blomhoffii, "Mamushi" in Japanese) were treated with an uniformly scheduled therapy from 1990 and 1994.
ANDO, SEIICHI +5 more
core
Identification of presynaptic neurotoxin complexes in the venoms of three Australian copperheads (Austrelaps spp.) and the efficacy of tiger snake antivenom to prevent or reverse neurotoxicity [PDF]
The venom of the Australian lowlands copperhead, Austrelaps superbus, produces significant and potentially lethal neurotoxic paralysis in cases of clinical envenomation. However, little is known about the neurotoxic components within this venom or venoms
Marcon, F, Nicholson, GM
core +1 more source
The toxin, previously described as a “non-toxic” toxin, was isolated from the scorpion venom of Tityus serrulatus (Ts), responsible for the most severe and the highest number of accidents in Brazil.
Manuela B. Pucca +5 more
doaj +1 more source
Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis
ABSTRACT Quantitative systems pharmacology (QSP) models offer a useful platform to integrate drug pharmacology with knowledge about biological mechanisms across multiple scales and data sources into a unified quantitative framework. This makes them invaluable to address many relevant questions in drug research and development.
Johannes Tillil +2 more
wiley +1 more source
In the present study, Heterometrus fastigiousus venom (HFV) was employed as antigen to produce species-specific scorpion antivenom (SAV) in albino mice (NIH) strain.
MK Chaubey
doaj +1 more source
Understanding Consumer Attitudes and Awareness After Admission to a Toxicology Unit
ABSTRACT Objective Involvement of consumers is critical in the management of deliberate self‐harm. We aimed to review the consumer experience in clinical toxicology patient management and research. Methods An anonymous, consenting non‐consecutive 12‐question survey was administered to toxicology in‐patients between April 28th and October 14th 2025 ...
Ingrid Berling +3 more
wiley +1 more source
Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop [PDF]
BackgroundEnvenomation by crotaline snakes (rattlesnake, cottonmouth, copperhead) is a complex, potentially lethal condition affecting thousands of people in the United States each year.
Eric J Lavonas +11 more
core +4 more sources
Envenomation by the madagascan colubrid snake, Ithycyphus miniatus
We report two cases of envenomation by a Madagascan opisthoglyphous snake, Ithycyphus miniatus. In both cases, the snake bit the finger of a human who was preparing an experiment by tying a string around the snake body.
A. Mori, T. Mizuta
doaj +1 more source
Massive Acute Pulmonary Edema and Cardiogenic Shock after Scorpion Envenomation in a Young Patient with No Cardiovascular Risk Factor [PDF]
Machihudé Pio +56 more
openalex +1 more source

