Results 21 to 30 of about 3,125 (178)

Centipede envenomation [PDF]

Wilderness & Environmental Medicine, 2001
Five episodes of envenomation by centipedes in 2 patients are reported. These arthropods are fast-moving, frightening in appearance to some, and may display aggressive behavior. However, stings from these centipedes, like most found worldwide, caused no serious morbidity or mortality.
S P, Bush, B O, King, R L, Norris, S A, Stockwell   +3 more
openaire   +2 more sources

Secreted Phospholipases A2 of Snake Venoms: Effects on the Peripheral Neuromuscular System with Comments on the Role of Phospholipases A2 in Disorders of the CNS and Their Uses in Industry

Toxins, 2013
Neuro- and myotoxicological signs and symptoms are significant clinical features of envenoming snakebites in many parts of the world. The toxins primarily responsible for the neuro and myotoxicity fall into one of two categories—those that bind to and ...
John B. Harris, Tracey Scott-Davey
doaj   +1 more source

Cost of Manufacturing for Recombinant Snakebite Antivenoms

Frontiers in Bioengineering and Biotechnology, 2020
Snakebite envenoming is a neglected tropical disease that affects millions of people across the globe. It has been suggested that recombinant antivenoms based on mixtures of human monoclonal antibodies, which target key toxins of medically important ...
Timothy Patrick Jenkins, Andreas Hougaard Laustsen   +1 more
doaj   +1 more source

Profiling the Murine Acute Phase and Inflammatory Responses to African Snake Venom: An Approach to Inform Acute Snakebite Pathology

Toxins, 2022
Snake envenoming causes rapid systemic and local effects that often result in fatal or long-term disability outcomes. It seems likely that acute phase and inflammatory responses contribute to these haemorrhagic, coagulopathic, neurotoxic, nephrotoxic and
Jaffer Alsolaiss, Chloe A. Evans, George O. Oluoch, Nicholas R. Casewell, Robert A. Harrison   +4 more
doaj   +1 more source

Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom

Toxins, 2018
There is an unmet need for economical snakebite therapies with long shelf lives that are effective even with delays in treatment. The orally bioavailable, heat-stable, secretory phospholipase A2 (sPLA2) inhibitor, LY333013, demonstrates antidotal ...
Matthew R. Lewin, José María Gutiérrez, Stephen P. Samuel, María Herrera, Wendy Bryan-Quirós, Bruno Lomonte, Philip E. Bickler, Tommaso C. Bulfone, David J. Williams   +8 more
doaj   +1 more source

Mesenchymal Stromal Cell-Based Therapies as Promising Treatments for Muscle Regeneration After Snakebite Envenoming

Frontiers in Immunology, 2021
Snakebite envenoming is a global neglected disease with an incidence of up to 2.7 million new cases every year. Although antivenoms are so-far the most effective treatment to reverse the acute systemic effects induced by snakebite envenoming, they have a
E. Eduardo Sanchez-Castro, Cecilia Pajuelo-Reyes, Rebeca Tejedo, Bárbara Soria-Juan, Bárbara Soria-Juan, Rafael Tapia-Limonchi, Etelvina Andreu, Etelvina Andreu, Ana B. Hitos, Ana B. Hitos, Franz Martin, Franz Martin, Franz Martin, Gladys M. Cahuana, Gladys M. Cahuana, Clara Guerra-Duarte, Thamyres C. Silva de Assis, Francisco J. Bedoya, Francisco J. Bedoya, Francisco J. Bedoya, Bernat Soria, Bernat Soria, Bernat Soria, Bernat Soria, Carlos Chávez-Olórtegui, Juan R. Tejedo, Juan R. Tejedo, Juan R. Tejedo, Juan R. Tejedo   +28 more
doaj   +1 more source

Bothrops lanceolatus Envenoming in Martinique: A Historical Perspective of the Clinical Effectiveness of Bothrofav Antivenom Treatment

Toxins
Bothrofav, a monospecific antivenom, was introduced in June 1991 and has shown excellent effectiveness against life-threatening and thrombotic complications of Bothrops lanceolatus envenoming. Because of the reoccurrence of cerebral stroke events despite
Dabor Resiere, Jonathan Florentin, Hossein Mehdaoui, Hatem Kallel, Veronique Legris-Allusson, Papa Gueye, Remi Neviere   +6 more
doaj   +1 more source

Priority Actions and Progress to Substantially and Sustainably Reduce the Mortality, Morbidity and Socioeconomic Burden of Tropical Snakebite

Toxins, 2016
The deliberations and conclusions of a Hinxton Retreat convened in September 2015, entitled “Mechanisms to reverse the public health neglect of snakebite victims” are reported.
Robert A. Harrison, José María Gutiérrez   +1 more
doaj   +1 more source

Envenoming by a Marine Blood Worm (Glycera)

Toxins, 2022
Bites from venomous marine annelid ‘bloodworms’ (e.g., Glycera spp.) do not appear to have been described in the medical literature despite being seemingly well-known to bait diggers and fishermen.
Daniela M. Durkin, Alison N. Young, Kent Khtikian, Zuzana Karjala, Arin L. Isenstein, Bryan G. Fry, Matthew R. Lewin   +6 more
doaj   +1 more source

Concepts for point-of-care ultrasound training in low resource settings: a scoping review

The Ultrasound Journal
Background Point-of-care ultrasound (POCUS) is a potent diagnostic tool especially in resource-limited settings. The implementation of POCUS diagnostics requires adequate training of POCUS operators.
Friedrich Eppel, Friederike Hunstig, Sabine Bélard, Benno Kreuels   +3 more
doaj   +1 more source