Results 31 to 40 of about 5,615 (213)

Bothrops lanceolatus Envenoming in Martinique: A Historical Perspective of the Clinical Effectiveness of Bothrofav Antivenom Treatment

Toxins
Bothrofav, a monospecific antivenom, was introduced in June 1991 and has shown excellent effectiveness against life-threatening and thrombotic complications of Bothrops lanceolatus envenoming. Because of the reoccurrence of cerebral stroke events despite
Dabor Resiere, Jonathan Florentin, Hossein Mehdaoui, Hatem Kallel, Veronique Legris-Allusson, Papa Gueye, Remi Neviere   +6 more
doaj   +1 more source

Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom

Toxins, 2018
There is an unmet need for economical snakebite therapies with long shelf lives that are effective even with delays in treatment. The orally bioavailable, heat-stable, secretory phospholipase A2 (sPLA2) inhibitor, LY333013, demonstrates antidotal ...
Matthew R. Lewin, José María Gutiérrez, Stephen P. Samuel, María Herrera, Wendy Bryan-Quirós, Bruno Lomonte, Philip E. Bickler, Tommaso C. Bulfone, David J. Williams   +8 more
doaj   +1 more source

Ocular sequelae of snakebite envenoming:a review of the indirect effects of snakebite envenoming on the eye [PDF]

, 2023
Snakebite envenoming is a major public health issue in developing, often agricultural-based, tropical countries, which causes substantial mortality and morbidity.
Vonk, Freek J., Wisse, Robert P.L., vanThiel, Jory, Wouters, Roel M., Jalink, Maarten B., van Thiel, Jory   +5 more
core   +1 more source

Concepts for point-of-care ultrasound training in low resource settings: a scoping review

The Ultrasound Journal
Background Point-of-care ultrasound (POCUS) is a potent diagnostic tool especially in resource-limited settings. The implementation of POCUS diagnostics requires adequate training of POCUS operators.
Friedrich Eppel, Friederike Hunstig, Sabine Bélard, Benno Kreuels   +3 more
doaj   +1 more source

Priority Actions and Progress to Substantially and Sustainably Reduce the Mortality, Morbidity and Socioeconomic Burden of Tropical Snakebite

Toxins, 2016
The deliberations and conclusions of a Hinxton Retreat convened in September 2015, entitled “Mechanisms to reverse the public health neglect of snakebite victims” are reported.
Robert A. Harrison, José María Gutiérrez   +1 more
doaj   +1 more source

Bee Venom Induces Acute Inflammation through a H₂O₂-Mediated System That Utilizes Superoxide Dismutase

Toxins, 2022
Venoms from venomous arthropods, including bees, typically induce an immediate local inflammatory response; however, how venoms acutely elicit inflammatory response and which components induce an inflammatory response remain unknown.
Kwang-Sik Lee, Bo-Yeon Kim, Min-Ji Park, Yijie Deng, Jin-Myung Kim, Yun-Hui Kim, Eun-Jee Heo, Hyung-Joo Yoon, Kyeong-Yong Lee, Yong-Soo Choi, Byung-Rae Jin   +10 more
doaj   +1 more source

Echis ocellatus Venom-Induced Reproductive Pathologies in Rat Model; Roles of Oxidative Stress and Pro-Inflammatory Cytokines

Toxins, 2022
This study reported reproductive pathologies associated with Echis ocellatus venom in animal model. Twenty male Wistar rats with body weight between 180 and 220 g were selected randomly into two groups (n = 10).
Babafemi Siji Ajisebiola, Priscilla Ifeoluwa Alamu, Adewale Segun James, Akindele Oluwatosin Adeyi   +3 more
doaj   +1 more source

No gain from pain: Lack of nociceptor activation suggests no adaptation for defence in the evolution of European viper venoms

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Snake venoms show variability in composition at all taxonomic levels, both within and between species, and the selective pressures underlying this variation have long been debated.
Bálint Üveges, Samuel D. Robinson, Vanessa Schendel, Edvárd Mizsei, Ana Ćuriċ, Maria Dimaki, Vincenzo Ferri, Silviu Petrovan, Andrea V. Pozzi, Tihomir Radonjiċ, Tibor Sos, Jeffrey W. Streicher, Alexandru Strugariu, Emina Šunje, Ștefan Zamfirescu, Oleksandr Zinenko, Irina Vetter, Wolfgang Wüster   +17 more
wiley   +1 more source

Crotalus Durissus Ruruima: Current Knowledge on Natural History, Medical Importance, and Clinical Toxinology

Frontiers in Immunology, 2021
Crotalus durissus ruruima is a rattlesnake subspecies mainly found in Roraima, the northernmost state of Brazil. Envenomings caused by this subspecies lead to severe clinical manifestations (e.g.
Manuela B. Pucca, Paulo Sérgio Bernarde, Anderson Maciel Rocha, Patrik F. Viana, Raimundo Erasmo Souza Farias, Felipe A. Cerni, Felipe A. Cerni, Isadora S. Oliveira, Isabela G. Ferreira, Eliseu A. Sandri, Jacqueline Sachett, Jacqueline Sachett, Fan Hui Wen, Vanderson Sampaio, Andreas H. Laustsen, Marco A. Sartim, Marco A. Sartim, Wuelton M. Monteiro, Wuelton M. Monteiro   +18 more
doaj   +1 more source

Pathways to Care for Patients With Severe Chronic NCDs: A Cross‐Sectional Survey of Inpatients in Neno Malawi

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Severe chronic non‐communicable diseases (NCDs) place a significant burden on low‐ and middle‐income countries (LMICs), where overburdened and underprepared health systems lead to misdiagnosis, treatment delays and poor outcomes.
Chantelle Boudreaux, Maryam Mansoor, Moses Banda Aron, Medson Boti, Gene Bukhman, Stellar Chibvunde, Kingsley Kanzoole, Kenwood Kumwenda, Henry Ndindi, Junious Mabo Sichali, Todd Ruderman, Ada Thapa, Alma J. Adler, Emily B. Wroe   +13 more
wiley   +1 more source