Results 91 to 100 of about 1,454,677 (334)

Attempted DNA extraction from a Rancho La Brea Columbian mammoth (Mammuthus columbi): prospects for ancient DNA from asphalt deposits. [PDF]

, 2014
Fossil-bearing asphalt deposits are an understudied and potentially significant source of ancient DNA. Previous attempts to extract DNA from skeletons preserved at the Rancho La Brea tar pits in Los Angeles, California, have proven unsuccessful, but it ...
Farrell, Aisling B, Gold, David A, Harris, John M, Jacobs, David K, Robinson, Jacqueline, Thalmann, Olaf   +5 more
core   +1 more source

Environmental DNA test validation guidelines.

, 2022
These Environmental DNA test validation guidelines provide harmonised quality control and minimum standard considerations for developing or validating eDNA/eRNA assays for the purpose of single-species or multi-species detection. This document is a comprehensive guide for the development and use of eDNA/eRNA tests, recommended and curated by eDNA ...
De Brauwer, M., Chariton, A., Clarke, L.J., Cooper, M.K., DiBattista, J., Furlan, E., Giblot-Ducray, D., Gleeson, D., Harford, A., Herbert, S., MacDonald, A.J., Miller, A., Montgomery, K., Mooney, T., Noble, L.M., Rourke, M., Sherman, C.D.H., Stat, M., Suter, L., West, K.M., White, N., Villacorta-Rath, C., Zaiko, A., Trujillo-Gonzalez, A.   +23 more
openaire   +3 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

The complete mitochondrial genome of the invasive cyanobacteriosponge Terpios hoshinota (Demospongiae, Suberitida, Suberitidae)

Mitochondrial DNA. Part B. Resources, 2023
The cyanobacteriosponge Terpios hoshinota occurs on tropical reefs throughout the Indo-Pacific. The species encrusts live coral, and other benthos, and is considered a pest species that can threaten the health and productivity of locally native benthic ...
Zoe T. Richards, Hiroki Kise, Katrina M. West   +2 more
doaj   +1 more source

Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions. [PDF]

, 2014
Endogenous metabolism, environmental exposure, and treatment with some chemotherapeutic agents can all give rise to DNA alkylation, which can occur on the phosphate backbone as well as the ring nitrogen or exocyclic nitrogen and oxygen atoms of ...
Cai, Qian, Wang, Pengcheng, Wang, Yinsheng, Zhai, Qianqian   +3 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Insight into Invertebrate Community in Solonchak Soil Type Using EDNA Metabarcoding – A Pilot Study

Contemporary Agriculture
Solonchaks are soils characterized by high concentrations of soluble salts. These soils form unique ecosystems that provide habitats for organisms adapted to such extreme conditions.
Lazić Cvijeta, Stefanović Milomir, Tubić Nataša Kočiš, Kuzmanović Ana, Radnović Dragan, Tamindžija Dragana, Milić Stanko, Vasin Jovica, Ninkov Jordana, Djan Mihajla   +9 more
doaj   +1 more source

Environmental DNA for the enumeration and management of Pacific salmon [PDF]

Molecular Ecology Resources, 2018
AbstractPacific salmon are a keystone resource in Alaska, generating annual revenues of well over ~US$500 million/year. Due to their anadromous life history, adult spawners distribute amongst thousands of streams, posing a huge management challenge.
Taal Levi, Jennifer M. Allen, Douglas W. Yu, Douglas W. Yu, Douglas W. Yu, Joshua R. Russell, David A. Tallmon, Donovan A. Bell, Chunyan Yang, Scott C. Vulstek, John E. Joyce   +10 more
openaire   +5 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Genomic resources for the monitoring and management of Tometes trilobatus, Hoplias aimara and Myloplus rhomboidalis, three exploited freshwater fish species in French Guiana

Knowledge and Management of Aquatic Ecosystems
The Neotropical region, hosts a quarter of all freshwater fish species, while providing important food resources for local human populations. The management of neotropical freshwater ecosystems is thus of primary importance for both biodiversity ...
Condachou Céline, Cuenot Yves, Pigeyre Laetitia, Covain Raphael, Vigouroux Régis, Brosse Sébastien, Murienne Jérôme   +6 more
doaj   +1 more source