Results 111 to 120 of about 14,325,844 (399)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Integrating research, surveillance, and practice in environmental public health tracking. [PDF]

, 2006
The Centers for Disease Control and Prevention in the U.S. Department of Health and Human Services is working with selected state and local health departments, academic centers, and others to develop an environmental public health tracking initiative to ...
Balmes, John R, Buffler, Patricia A, Kyle, Amy D, Lee, Philip R   +3 more
core  

The National Nanotechnology Initiative Approach to Environment, Health, and Safety: A Model for Future Science Investments

Federal History, 2016
This article discusses the very recent story about the new science of nanotechnology and the careful and clear-headed efforts to regulate it. Nanotechnology offers great promise in numerous applications, including national security, but can also raise ...
Brandi L. Schottel, Barbara Karn
doaj  

Poluição veicular e saúde da população: uma revisão sobre o município de São Paulo (SP), Brasil Traffic related air pollution and population health: a review about São Paulo (SP), Brazil

Revista Brasileira de Epidemiologia, 2011
INTRODUÇÃO: A poluição do ar é um problema importante para o município de São Paulo, cuja maior fonte são os veículos. Cerca de 11 milhões de habitantes estão expostos a essa poluição.
Giovana Iara Ferreira Moser de Toledo, Adelaide Cássia Nardocci   +1 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Determinación ambiental de la salud: un reto para Colombia /Environmental health determination: a challenge for Colombia

Revista Facultad Nacional de Salud Pública, 2013
La sociedad actual se ha visto abocada a dar respuestas articuladas y con una visión integradora a los temas de condiciones de salud de la población, el cuidado de los recursos naturales y la generación de mecanismos de crecimiento económico ...
Juan C. García-Ubaque, Martha L. Vaca B, César A. García-Ubaque   +2 more
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Public Health Burden of E-waste in Africa

Journal of Health and Pollution, 2019
Background. Environmental impacts from informal e-waste recycling are increasing in Africa. E-waste handling and disposal exposes people to highly toxic cocktails of heavy metals, brominated flame retardants, non-dioxin-like polychlorinated biphenyls ...
Orish Ebere Orisakwe, Chiara Frazzoli, Cajetan Elochukwu Ilo, Benjamin Oritsemuelebi   +3 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source