Results 51 to 60 of about 2,712,876 (308)

The hypoxic transcription factor KlMga2 mediates the response to oxidative stress and influences longevity in the yeast Kluyveromyces lactis [PDF]

open access: yes, 2019
Hypoxia is defined as the decline of oxygen availability, depending on environmental supply and cellular consumption rate. The decrease in O2 results in reduction of available energy in facultative aerobes.
Bianchi, Michele M   +7 more
core   +1 more source

Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]

open access: yes, 2020
Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The apple of discord: can spider cocoons be equipped with antimicrobial factors?—a systematic review

open access: yesFrontiers in Zoology
The antimicrobial properties of spider silk have been a topic of scientific intrigue since ancient times. Despite extensive research, the question remains unresolved due to conflicting findings and methodological challenges.
Mateusz Glenszczyk   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Development of job demands, decision authority and social support in industries with different gender composition – Sweden, 1991–2013

open access: yesBMC Public Health, 2019
Background This study aims to explore the development of job demands, decision authority and social support within and between industries with different gender composition in Sweden between 1991 and 2013. Methods Cross-sectional data from 12 waves of the
Sara Cerdas   +3 more
doaj   +1 more source

Overexpression of beta-carotene hydroxylase enhances stress tolerance in Arabidopsis [PDF]

open access: yes, 2002
Plant stress caused by extreme environmental conditions is already a principal reason for yield reduction in crops. The threat of global environment change makes it increasingly important to generate crop plants that will withstand such conditions ...
Davison, P.A., Horton, P., Hunter, C.N.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Psychosocial work demands and physical workload decrease with ageing in blue-collar and white-collar workers: a prospective study based on the SLOSH cohort

open access: yesBMJ Open, 2019
Objectives Psychosocial work demands and physical workload are important causes of ill health. The dramatic demographic changes in society make it important to understand if such factors change with ageing, but this is presently not known. The purpose of
Hugo Westerlund   +3 more
doaj   +1 more source

Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone

open access: yesNature Communications, 2022
Cyclic-di-GMP transduces extracellular stimuli into intracellular responses to modulate important biological processes. Here, the authors show that AI-2 and bile salts induce cyclic-di-GMP synthesis via YeaJ and YedQ, respectively, to repress the T3SS ...
Shuyu Li   +13 more
doaj   +1 more source

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