Results 61 to 70 of about 2,712,876 (308)

Emerging connections between small RNAs and phytohormones [PDF]

, 2020
Small RNAs (sRNAs), mainly including miRNAs and siRNAs, are ubiquitous in eukaryotes. sRNAs mostly negatively regulate gene expression via (post-)transcriptional gene silencing through DNA methylation, mRNA cleavage, or translation inhibition.
Dubois, Marieke, Gonzalez Sanchez, Nathalie, Inzé, Dirk, Li, Ting   +3 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Two-polarized roles of transcription factor FOSB in lung cancer progression and prognosis: dependent on p53 status

Journal of Experimental & Clinical Cancer Research
Background Activator protein-1 (AP-1) represents a transcription factor family that has garnered growing attention for its extensive involvement in tumor biology.
Hongchao Zhang, Guopei Zhang, Mingyang Xiao, Su Cui, Cuihong Jin, Jinghua Yang, Shengwen Wu, Xiaobo Lu   +7 more
doaj   +1 more source

Development and Validation of a Novel Method Using QuEChERS and UHPLC-MS-MS for the Determination of Multiple Emerging Fungicides in Surface Waters

Separations
The increasing global reliance on pesticides for agricultural pest control has raised significant environmental concerns, particularly due to inadequate monitoring of emerging chemicals in surface waters.
Pulasthi Serasinghe, Deni Taleski, Hao T. K. Nguyen, Dayanthi Nugegoda, Vincent Pettigrove   +4 more
doaj   +1 more source

A novel approach for tailoring pesticide screens for monitoring regional aquatic ecosystems

Environmental Advances, 2022
Pesticide monitoring programs are required to understand pesticide contamination in the environment. They can be used to compare existing water quality guidelines and associated their presence with activities related to catchments.
Pulasthi Serasinghe, Hao T.K Nguyen, Thishakya De Silva, Dayanthi Nugegoda, Vincent Pettigrove   +4 more
doaj   +1 more source

Behavioural stress responses predict environmental perception in European sea bass (Dicentrarchus labrax) [PDF]

, 2014
Individual variation in the response to environmental challenges depends partly on innate reaction norms, partly on experience-based cognitive/emotional evaluations that individuals make of the situation. The goal of this study was to investigate whether
A Sih, AM Bell, AM Bell, B Chatain, C Brown, Catarina I. M. Martins, CIM Martins, CIM Martins, Claudia Mettke-Hofmann, DL Sinn, DS Wilson, E Fanouraki, E Rink, F Huntingford, JM Koolhaas, KN Laland, KP Chandroo, KR Scherer, LS Demski, LU Sneddon, M Endo, Marco Cerqueira, Maria-Filipa Castanheira, MC Appleby, MF Castanheira, MF Castanheira, MJ Herrero, MS Dawkins, P Mathur, PIM Silva, R Bshary, RD Kirkden, RF Benus, RJ Arends, RJ Egan, Rui F. Oliveira, S Winberg, S Yue, Sandie Millot, T Backström, TM Tzschentke, TW Pike, W Korzan, Ø Øverli, Ø Øverli, Ø Øverli, Øyvind Øverli   +46 more
core   +6 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Chronic sleep deprivation disturbs energy balance modulated by suprachiasmatic nucleus efferents in mice

BMC Biology
Background Epidemiologic researches show that short sleep duration may affect feeding behaviors resulting in higher energy intake and increased risk of obesity, but the further mechanisms that can interpret the causality remain unclear.
Tingting Du, Shuailing Liu, Honghong Yu, Tian Hu, Lina Huang, Lanyue Gao, Lihong Jia, Jiajin Hu, Yang Yu, Qi Sun   +9 more
doaj   +1 more source

Cardiac autonomic and cortisol stress responses to real operations in surgeons: relationship with individual psychobiological characteristics and experience

BioPsychoSocial Medicine, 2023
Background Surgeons are exposed to high levels of intraoperative stress, which could compromise their psychological well-being in the long term. This study aimed at exploring the effects of real operations on the activity of stress response systems (i.e.,
Luca Carnevali, Elena Bignami, Sara Gambetta, Margherita Barbetti, Matteo Procopio, Antonio Freyrie, Paolo Carbognani, Luca Ampollini, Andrea Sgoifo   +8 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source