Results 81 to 90 of about 2,712,876 (308)

Sensing of autoinducer-2 by functionally distinct receptors in prokaryotes

Nature Communications, 2020
The small molecule AI-2 acts as a quorum sensing signal, mediating communication within and between many bacterial species. Here, the authors identify a new type of AI-2 receptor, consisting of a dCACHE domain that is present in many bacterial and ...
Lei Zhang, Shuyu Li, Xiaozhen Liu, Zhuo Wang, Mei Jiang, Ruiying Wang, Laigong Xie, Qinmeng Liu, Xiaorong Xie, Daohan Shang, Mengyun Li, Zhiyan Wei, Yao Wang, Chengpeng Fan, Zhao-Qing Luo, Xihui Shen   +15 more
doaj   +1 more source

Influence of Exercise Environment on Stress and Affect in Sedentary Adults: A Comparison of Indoor and Natural Environments [PDF]

, 2018
The national need for increased physical activity, especially among sedentary populations, has been well documented. The need now is for fitness programs to be more effective at encouraging individuals to adopt and maintain a physically active lifestyle.
Snider, Rachel M.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Grab Sampling or Passive Samplers? A Comparative Approach to Water Quality Monitoring

Molecules
Pesticide contamination poses significant threats to both humans and the environment, with residues frequently detected in surface waters worldwide.
Caterina Cacciatori, Jackie Myers, Giulio Mariani, Bernd Manfred Gawlik, Vincent Pettigrove   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The impact of environmental resources on the stress process : encouraging positive outcomes in the workplace : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Turitea, New Zealand [PDF]

, 2008
The present study investigated resources in the organisational environment which would increase the likelihood of positive outcomes from the stress process.
Van der Merwe, Anika
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Environmental changes and violent conflict [PDF]

, 2012
This letter reviews the scientific literature on whether and how environmental changes affect the risk of violent conflict. The available evidence from qualitative case studies indicates that environmental stress can contribute to violent conflict in ...
, , Baechler G, Baechler G, Ban K M, Bergholt D, Bernauer T, Bernauer T Böhmelt T Buhaug H Gleditsch N P Tribaldos T Weibust E B Wischnath G, Buhaug H, Dinar A, Esty D, Garfinkel M R, Gartzke E, Haavelmo T, Hauge W, Hendrix C, Hess G D, Homer-Dixon T, Homer-Dixon T, Kahl C H, Kalbhenn A, Knerr B, Koubi V, Laczko F, Lomborg B, Matthew R A Gaulin T, Moran D, Raleigh C, Russett B, Salehyan I, Simon J, Skaperdas S, Spillman K R, Stern N, Suhrke A, Tamondong-Helin S, Theisen O M, Thomas Bernauer, Tobias Böhmelt, Vally Koubi, Wolf A   +40 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source