Results 81 to 90 of about 1,427,148 (344)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

NEW DIPPING TREATMENTS TO CONTROL ENZYMATIC BROWNING OF APPLES DURING DRYING [PDF]

, 2018
The present experimental activity aims to improve the quality of apple wedges (var. Golden delicious) during 8-h drying at 60°C, using dipping treatments in fruit juices (orange, pineapple, green kiwifruit, yellow kiwifruit) and/or herbal teas (green tea,
Riccardo, Massantini, Roberto, Moscetti, Silvia, Stellati   +2 more
core  

Physical Treatments and Propolis Extract to Enhance Quality Attributes of Fresh-Cut Mixed Vegetables [PDF]

, 2016
The impact of individual and combined application of propolis extract (PE) plus ultrasound (ULT) or thermal treatment (TT) on the microbiological, nutritional, physicochemical and sensory quality of fresh-cut mixed vegetables for soup (celery, leek and ...
Alvarez, María Victoria, Goyeneche, Rosario, Moreira, Maria del Rosario, Ponce, Alejandra Graciela   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Oxidative Stress Associated with Chilling Injury in Immature Fruit: Postharvest Technological and Biotechnological Solutions [PDF]

, 2017
Immature, vegetable-like fruits are produced by crops of great economic importance, including cucumbers, zucchini, eggplants and bell peppers, among others. Because of their high respiration rates, associated with high rates of dehydration and metabolism,
Carvajal Moreno, Fátima, Garrido Garrido, María Dolores, Jamilena Quesada, Manuel, Manzano Medina, Susana, Palma, Francisco, Valenzuela Manjón-Cabeza, Juan Luis   +5 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Sweet cherry:composition, postharvest preservation, processing and trends for its future use [PDF]

, 2016
Background Sweet cherries (Prunus avium L.) are a nutritious fruit which are rich in polyphenols and have high antioxidant potential. Most sweet cherries are consumed fresh and a small proportion of the total sweet cherries production is value added to ...
Chockchaisawasdee, Suwimol, Golding, John B., Papoutsis, Konstantinos, Stathopoulos, Costas E., Vuong, Quan V.   +4 more
core   +2 more sources

Application of citronella and rose hydrosols reduced enzymatic browning of fresh-cut taro.

Journal of food biochemistry, 2020
Hydrosols are byproducts produced by steam distillation of aromatic plant materials. Previous studies reported hydrosols owned effectively inhibitory effects on microbials, but few focused on the effects in reducing enzymatic browning of fresh-cut ...
Yanhui Xiao, Jinming He, J. Zeng, Xiao Yuan, Zhenming Zhang, Bin Wang   +5 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evaluation of enzymatic browning in fresh-cut apple slices applying a multispectral vision system [PDF]

, 2010
n this study a vision system was applied for assessing enzymatic browning evolution in fresh-cut apples slices stored at 7.5 °C and 85 % HR. Twenty-four slices were analyzed per day: at zero time and after storage for 1 , 3 ,7 and 9 days.
Diezma Iglesias, Belen, Galleguillos, Pamela, Lleó García, Lourdes, Lunadei, Loredana   +3 more
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