Results 31 to 40 of about 1,019,197 (164)
Activation of the Bradykinin System by Angiotensin-Converting Enzyme Inhibitors
European Journal of Inflammation, 2010 The Bradykinin (BK) system has a very significant role in the regulation of blood pressure (BP). Hence, reduced activity of BK receptors mediated via decreased circulating endogenous kinin might explain the cause of high BP.
J.N. Sharma
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Subcellular localization of hexadecanedioic acid activation in human liver
Journal of Lipid Research, 1974 The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 μmole/min/g wet wt of tissue, about 10% of that for palmitic acid ...
Jon Elling Pettersen, Magne Aas
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Frontiers in Physiology, 2023 Introduction: The actin regulatory protein, cofilin plays a key signaling role in many cells for numerous cellular responses including in proliferation, development, motility, migration, secretion and growth.
Irene Ramos-Alvarez +3 more
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MoleculesWe report on the synthesis of two fluorescent probes which can be activated by β-Galactosidase (β-Gal) enzymes and/or light. The probes contained 2-nitro-4-oxybenzyl and 3-nitro-4-oxybenzyl fragments, with β-Gal residues linked to C-4.
Taukeer A. Khan +4 more
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Covalent immobilization of glucoamylase enzyme onto chemically activated surface of κ-carrageenan
Bulletin of the National Research Centre, 2019 Background Glucoamylase enzyme is one of the most important enzymes. It catalyzes the hydrolysis of starch into soluble sugars. It was covalently immobilized onto κ-carrageenan gel beads after activation by using polyethylenimine (PEI) followed by ...
Mohamed E. Hassan +2 more
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Recent Trends in Enzyme Inhibition and Activation in Drug Design
Molecules, 2020 It is known that enzymes are involved in many pathological conditions, such as inflammation, diabetes, microbial infections, HIV, neoplastic, neglected diseases and others [...]
Athina Geronikaki
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Ack1: activation and regulation by allostery. [PDF]
PLoS ONE, 2013 The non-receptor tyrosine kinase Ack1 belongs to a unique multi-domain protein kinase family, Ack. Ack is the only family of SH3 domain containing kinases to have an SH3 domain following the kinase domain; others have their SH3 domains preceding the ...
Ketan S Gajiwala +4 more
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Frontiers in Molecular Neuroscience, 2022 Multisite phosphorylation of guanylyl cyclase (GC)-A, also known as NPR-A or NPR1, is required for receptor activation by natriuretic peptides (NPs) because alanine substitutions for the first four GC-A phosphorylation sites produce an enzyme that cannot
Neil M. Otto, Lincoln R. Potter
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Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation.
PLoS ONE, 2012 Cysteine residues in insulin degrading enzyme have been reported as non-critical for its activity. We found that converting the twelve cysteine residues in rat insulin degrading enzyme (IDE) to serines resulted in a cysteine-free form of the enzyme with ...
Eun Suk Song +6 more
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Journal of Lipid Research, 2000 The sphingomyelinase (Sphmase) activity degrading sphingomyelin (Sphm) monolayers shows a slow-reaction latency period before exhibiting constant rate catalysis. These two kinetic regions are regulated independently by the lateral surface pressure and by
María Laura Fanani, Bruno Maggio
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