On the kinetic and allosteric regulatory properties of the ADP-glucose pyrophosphorylase from Rhodococcus jostii: An approach to evaluate glycogen metabolism in oleaginous bacteria [PDF]
, 2016 Rhodococcus spp. are oleaginous bacteria that accumulate glycogen during exponential growth. Despite the importance of these microorganisms in biotechnology, little is known about the regulation of carbon and energy storage, mainly the relationship ...
Alvarez, Hector Manuel +4 more
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In vivo activation of methyl-coenzyme M reductase by carbon monoxide
Frontiers in Microbiology, 2013 Methyl-coenzyme M reductase (MCR) from methanogenic archaea catalyzes the rate-limiting and final step in methane biosynthesis. Using coenzyme B (CoBSH) as the two-electron donor, MCR reduces methyl-coenzyme M (CH3-SCoM) to methane and the mixed ...
Yuzhen eZhou +2 more
doaj +1 more source
Cold-Water Immersion Promotes Antioxidant Enzyme Activation in Elite Taekwondo Athletes
Applied Sciences, 2021 The aim of this study was to investigate the effect of cold-water immersion (CWI) on lipid peroxides and antioxidant enzymes in adult Taekwondo athletes after a match. A cross-sectional study was performed.
Eun-Hee Park +2 more
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Interactions between the endocrine and immune systems in locusts [PDF]
, 2003 The prophenoloxidase cascade in the haemolymph of mature adult Locusta migratoria migratorioides (R & F) is activated in response to injection of laminarin, a -1,3 glucan.
Chandrakant, S. +3 more
core +1 more source
Genome-scale architecture of small molecule regulatory networks and the fundamental trade-off between regulation and enzymatic activity [PDF]
, 2017 Metabolic flux is in part regulated by endogenous small molecules that modulate the catalytic activity of an enzyme, e.g., allosteric inhibition. In contrast to transcriptional regulation of enzymes, technical limitations have hindered the production of ...
Briars, Emma +6 more
core +2 more sources
A survey of orphan enzyme activities [PDF]
BMC Bioinformatics, 2007 Using computational database searches, we have demonstrated previously that no gene sequences could be found for at least 36% of enzyme activities that have been assigned an Enzyme Commission number. Here we present a follow-up literature-based survey involving a statistically significant sample of such "orphan" activities.
Peter D. Karp +2 more
openaire +4 more sources
Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia
Química Nova, 2006 Strategies that promote selective activation of prodrugs by enzymes can be divided into two major classes: 1) deliver of a monoclonal antibody-enzyme immunoconjugate that can recognize a specific antigen and promote the prodrug to a citotoxic drug, with ...
Lorena Blau +2 more
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Unraveling the activation mechanism of the potato tuber ADP-glucose pyrophosphorylase. [PDF]
PLoS ONE, 2013 ADP-glucose pyrophosphorylase regulates the synthesis of glycogen in bacteria and of starch in plants. The enzyme from plants is mainly activated by 3-phosphoglycerate and is a heterotetramer comprising two small and two large subunits.
Carlos M Figueroa +6 more
doaj +1 more source
Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation [PDF]
, 2018 The E3 ligase parkin ubiquitinates outer mitochondrial membrane proteins during oxidative stress and is linked to early-onset Parkinson’s disease. Parkin is autoinhibited but is activated by the kinase PINK1 that phosphorylates ubiquitin leading to ...
Aguirre, Jacob D. +9 more
core +1 more source
Determination of enzyme activities with the enzyme thermistor unit [PDF]
FEBS Letters, 1979 Practically all enzyrnic reactions can be followed by calorimetry. Important advantages of this technique are that the optical properties of the sample do not interfere with the measurements and that no auxiliary enzymic reactions are required such as those leading to changes in optical absorption that can be followed spectrophotometrically.
Bengt Danielsson, Klaus Mosbach
openaire +3 more sources