Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity [PDF]
Insulin degrading enzyme (IDE) is a dimeric M16A zinc metalloprotease that degrades amyloidogenic peptides diverse in shape and sequence, including insulin and amyloid-β, to prevent toxic amyloid fibril formation.
Jordan M Mancl +9 more
doaj +2 more sources
Catalase Specifically Binds Antipsychotic Clozapine: Experimental and In Silico Insights into Interactions, Complex Stability, and Dose-Dependent Enzyme Activity Modulation [PDF]
Oxidative stress is intrinsically linked to mental disorders, involving an imbalance between reactive species and antioxidant defenses, where catalase is an essential, ubiquitous antioxidant enzyme.
Tamara Vasović +6 more
doaj +2 more sources
Enzyme-like activity of nanomaterials
In modern conditions, nanomaterials, especially nanoparticles of metals and nonmetals, are increasingly used in various industries. Due to their unique properties, in particular, the ability of nanoparticles to exhibit an enzyme-like effect they are ...
S. I. Tsekhmistrenko +7 more
doaj +1 more source
Enhanced Enzyme Activity with Ferritin Nanocages
I n this study, a novel enzyme system based on ferritin nanocages was designed. α-Amylase was covalently crosslinked on surface of ferritin nanocages by EDC/NHS. The activity of immobilized enzyme was monitored by using UV-vis spectrophotometer.
Eylem Turan
doaj +1 more source
Following Enzyme Activity with Infrared Spectroscopy
Fourier transform infrared (FTIR) spectroscopy provides a direct, "on-line" monitor of enzymatic reactions. Measurement of enzymatic activity is based on the fact that the infrared spectra of reactants and products of an enzymatic reaction are usually ...
Saroj Kumar, Andreas Barth
doaj +1 more source
Enzyme activities in activated sludge flocs [PDF]
This study quantified the activities of enzymes in extracellular polymeric substances (EPS) and in pellets. Seven commonly adopted extraction schemes were utilized to extract from aerobic flocs the contained EPS, which were further categorized into loosely bound (LB) and tightly bound (TB) fractions.
Yu, Guang-Hui +3 more
openaire +2 more sources
Enzyme activity in the crowded milieu.
The cytosol of a cell is a concentrated milieu of a variety of different molecules, including small molecules (salts and metabolites) and macromolecules such as nucleic acids, polysaccharides, proteins and large macromolecular complexes.
Tobias Vöpel, George I Makhatadze
doaj +1 more source
The Effects of Heavy Metals and Molasses on Enzyme Activity of Candida Yeast
Lipases are mainly applied in the food, abluent and medicine industries. Through the high production costs of lipase enzymes for industrial applications, cheap and eco-friendly enzyme production has gained great importance in recent years.
Unsal Açıkel, Gülşah Başkan
doaj +1 more source
Enzyme Immobilization Onto Biochar Produced by the Hydrothermal Carbonization of Biomass
For improving enzyme utilization in biotechnological processes, process costs have to be reduced, enzyme stability during industrial processes should be enhanced, and the recycle and reuse step should be favorable.
Mateja Primožič +5 more
doaj +1 more source
Production of polygalacturonase by Aspergillus niger BC23 isolated from Irvingia gabonensis (African mango) fruit [PDF]
Polygalacturonase was produced from Aspergillus niger BC 23 which was isolated from spoiled Irvingia gabonensis fruit. The influence of carbon substrates on enzyme production showed that the medium containing sucrose produced a maximum enzyme ...
Ogbonnaya Nwokoro +1 more
doaj +1 more source

