Results 21 to 30 of about 365,104 (302)

Astroenzymology – the environmental limits of enzyme activity [PDF]

, 2003
Using organisms from extreme terrestrial environments as models for extraterrestrial life may lead us to underestimate the range of environments that life may inhabit.
Daniel, Roy M., Roy Daniel
core   +1 more source

High-efficient production of mushroom polyketide compounds in a platform host Aspergillus oryzae

Microbial Cell Factories, 2023
Background Orsellinic acid (2,4-dihydroxy-6-methylbenzoic acid, OA) and its structural analog o-Orsellinaldehyde, have become widely used intermediates in clinical drugs synthesis.
Haiyan Han, Chunyan Yu, Jianzhao Qi, Pengchao Wang, Peipei Zhao, Wenbing Gong, Chunliang Xie, Xuekui Xia, Chengwei Liu   +8 more
doaj   +1 more source

Research Progress on Fungal Sesterterpenoids Biosynthesis

Journal of Fungi, 2022
Sesterterpenes are 25-carbon terpenoids formed by the cyclization of dimethyl allyl diphosphate (DMAPP) and isopentenyl diphosphate (IPP) as structural units by sesterterpenes synthases.
Ping Zhang, Jianzhao Qi, Yingce Duan, Jin-ming Gao, Chengwei Liu   +4 more
doaj   +1 more source

Sesquiterpene synthases from Inonotus obliquus: functional characterization and β-farnesene production

Mycology
The medicinal mushroom Inonotus obliquus is renowned for producing a wide array of pharmacologically active terpenoids, yet the enzymatic basis for this diversity remains partially elusive.
Yingce Duan, Jiaxuan Liu, Zheyong Xue, Pengchao Wang, Jie Zhang, Chengwei Liu   +5 more
doaj   +1 more source

Enzyme Reactor Engineering

CHIMIA, 1975
Design procedures for enzyme reactors do not differ fundamentally from those of conventional catalytic reactors. Initially, the decision must be made whether continuous operation has economic advantages over batchwise processing. Generally, a continuous
Irving J. Dunn
doaj   +1 more source

Chelerythrine-Mediated Growth Inhibition and Resistance Mechanism in Bacillus tropicus

Microorganisms
Chelerythrine (CHE) is a naturally occurring benzophenanthridine alkaloid obtained from plants such as Chelidonium majus L. It has received notable attention in pharmacology and microbial control because of its broad-spectrum activity and marked anti ...
Jueyu Wang, Hongxia Wan, Wenqi Chai, Daizong Cui, Min Zhao   +4 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Mesocellular carbon foam with a bimodal structure and its use for enzyme immobilization [PDF]

, 2005
1
김학성, Alice Dohnalkova, 신채호, 현택환, 이진우, 김중배, Ja Hun Kwak, 이도훈, 나현빈, 김재윤, Jay W. Grate   +10 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Design of novel enzyme-catalyzed reactions linked to protein sequences for finding enzyme engineering targets [PDF]

, 2017
A key challenge in metabolic engineering is to find and to improve biosynthetic pathways that lead to the cellular production of a given industrial, pharmaceutical or specialty chemical compound.
Hatzimanikatis, Vassily, Mohammadi Peyhani, Homa, Peyhani, Homa Mohammadi, Hafner, Jasmin, Hafner, Jasmin Maria, Hadadi, Noushin   +5 more
core   +1 more source