A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn +7 more
wiley +1 more source
Semi-permeable nanocapsules of konjac glucomannan-chitosan for enzyme immobilization [PDF]
Carboxymethyl konjac glucomannan-chitosan (CKGM-CS) nanocapsules, spontaneously prepared under very mild conditions by electrostatic complexation, were used for immobilizing L-asparaginase.
Xia, B +6 more
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Dynamics of immobilized and native Escherichia coli dihydrofolate reductase by quasielastic neutron scattering [PDF]
The internal dynamics of native and immobilized Escherichia coli dihydrofolate reductase (DHFR) have been examined using incoherent quasielastic neutron scattering.
Smith, J.C. +15 more
core +1 more source
A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang +16 more
wiley +1 more source
Caracterização bioquímica de duas lipases mutantes de Staphylococcus xylosus e de uma esterase de Lactobacillus plantarum imobilizada em polipropileno [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2010As lipases e esterases pertencem ao grupo das hidrolases e são enzimas capazes de ...
Kolling, Deise Juliana
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Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Imobilização de lipase de Candida antarctica B em quitosana para obtenção de biodiesel por transesterificação do óleo de mamona [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaEste trabalho teve como objetivo principal estudar a imobilização de lipase comercial (Lipozyme CALB L) em esferas de ...
Cruz Júnior, Américo
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An overview of techniques in enzyme immobilization [PDF]
Immobilized enzymes have become the subject of considerable interest due to their excellent functional properties such as reusability, cost-effectiveness, and optimality during the past decades.
Moonil Kim, H H Nguyen
core +1 more source
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan +7 more
wiley +1 more source
BIOTECHNOLOGICAL EMPLOYMENT OF OLIVE OIL MILL WASTEWATERS FOR WATER REMEDIATION AND POTENTIAL BIODIESEL PRODUCTION [PDF]
Olive oil mill wastewaters (OMW) are dark-colored wastes characterized by high values of COD (chemical oxygen demand) and BOD (biological oxygen demand). OMW contains high amounts of organic and inorganic compounds.
Addorisio, Veria
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