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Enzyme inhibition in drug discovery and development. The good and the bad.
, 2010 Maria Paola Costi
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Recent Advances in Enzyme Inhibition: A Pharmacological Review
Current Enzyme Inhibition, 2023Enzyme inhibition is a crucial mechanism for regulating biological processes and developing therapeutic interventions. This pharmacological review summarizes recent advances in enzyme inhibition, focusing on key developments and their implications for ...
Kuldeep Singh +8 more
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Journal of Agricultural and Food Chemistry, 2020
Acetylcholinesterase inactivating compounds, such as organophosphate (OP) and carbamate (CM) pesticides, are widely used in agriculture to ensure sustainable production of food and feed.
Jing Cao +9 more
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Acetylcholinesterase inactivating compounds, such as organophosphate (OP) and carbamate (CM) pesticides, are widely used in agriculture to ensure sustainable production of food and feed.
Jing Cao +9 more
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2023
This chapter discusses enzyme inhibition. A major aspect of the regulation of enzyme activity and therefore of the balance of reaction rates in organisms is the possibility that a compound can inhibit the enzyme's action. The modulation of the activity of enzymes with effector molecules is essential for the coordination of the huge number of reactions ...
Pranati Das +4 more
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This chapter discusses enzyme inhibition. A major aspect of the regulation of enzyme activity and therefore of the balance of reaction rates in organisms is the possibility that a compound can inhibit the enzyme's action. The modulation of the activity of enzymes with effector molecules is essential for the coordination of the huge number of reactions ...
Pranati Das +4 more
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Food Chemistry, 2020
This study was the first to evaluate changes in isoflavone, amino acid, conjugated linoleic acid (CLA), antioxidant effect, and digestive enzyme inhibition during fermentation of soy-milk to soy-yogurt with L. brevis and L. plantarum.
C. Hwang +6 more
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This study was the first to evaluate changes in isoflavone, amino acid, conjugated linoleic acid (CLA), antioxidant effect, and digestive enzyme inhibition during fermentation of soy-milk to soy-yogurt with L. brevis and L. plantarum.
C. Hwang +6 more
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ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn.
Bioorganic chemistry (Print), 2019Achillea schischkinii Sosn. is an endemic plant species and it belongs to Asteraceae family. It is distributed widely in the Central and East Anatolia.
F. Türkan +4 more
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Enzyme induction and inhibition
Pharmacology & Therapeutics, 1990The rate and extent of drug metabolism significantly influences drug effect. Enzyme induction by increasing the metabolism of drugs may result in important drug interactions. Other implications of enzyme induction include alterations in the metabolism of endogenous substrates, vitamins and activity of extrahepatic enzyme systems. Similarly a wide range
M, Barry, J, Feely
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Food Chemistry, 2021
The inhibition of the α-amylase and α-glucosidase activity facilitates the maintenance of circulating glucose levels by decreasing the rate of blood sugar absorption.
Konstantinos Papoutsis +5 more
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The inhibition of the α-amylase and α-glucosidase activity facilitates the maintenance of circulating glucose levels by decreasing the rate of blood sugar absorption.
Konstantinos Papoutsis +5 more
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