Results 31 to 40 of about 6,711,495 (336)

Point-of-Care Portable 3D-Printed Multispectral Sensor for Real-Time Enzyme Activity Monitoring in Healthcare Applications

open access: yesBiosensors, 2023
Absorbance spectroscopy finds many biomedical and physical applications ranging from studying the atomic and molecular details of the analyte to determination of unknown biological species and their concentration or activity in the samples.
Antony Jesuraj, Umer Hassan
doaj   +1 more source

Alpha-Amylase and Alpha-Glucosidase Enzyme Inhibition and Antioxidant Potential of 3-Oxolupenal and Katononic Acid Isolated from Nuxia oppositifolia

open access: yesBiomolecules, 2019
Nuxia oppositifolia is traditionally used in diabetes treatment in many Arabian countries; however, scientific evidence is lacking. Hence, the present study explored the antidiabetic and antioxidant activities of the plant extracts and their purified ...
A. Alqahtani   +8 more
semanticscholar   +1 more source

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

open access: yesBMC Chemistry, 2019
Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik   +2 more
doaj   +1 more source

Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α-amylase, butyrylcholinesterase, and α-glycosidase enzymes.

open access: yesJournal of food biochemistry, 2019
Many taxa of Salvia genus have been used in herbal beverages, food flavoring, cosmetics, and pharmaceutical industry. In this paper, chemical compounds of Salvia eriophora (S.
E. Bursal   +5 more
semanticscholar   +1 more source

Models of enzyme inhibition and apparent dissociation constants from kinetic analysis to study the differential inhibition of aldose reductase [PDF]

open access: yes, 2022
In order to explain the negative slope of [Image: see text] versus inhibitor concentration observed in the study of epigallocatechin gallate acting as an inhibitor of aldose reductase, a kinetic analysis was performed to rationalise the phenomenon ...
Del-Corso, Antonella   +4 more
core   +1 more source

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

open access: yesBiomolecules, 2020
Caffeic acid (CA) and its derivatives caffeic acid phenethyl ester (CAPE) and chlorogenic acid (CGA) are phenolic compounds of plant origin with a wide range of biological activities. Here, we identify and characterize their inhibitory properties against
Liza Ulčakar, Marko Novinec
doaj   +1 more source

Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase

open access: yesMolecules, 2021
Based on the broad spectrum of biological activity of hydrazide–hydrazones, trifluoromethyl compounds, and clinical usage of cholinesterase inhibitors, we investigated hydrazones obtained from 4-(trifluoromethyl)benzohydrazide and various benzaldehydes ...
Martin Krátký   +4 more
doaj   +1 more source

ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn.

open access: yesBioorganic chemistry (Print), 2019
Achillea schischkinii Sosn. is an endemic plant species and it belongs to Asteraceae family. It is distributed widely in the Central and East Anatolia.
F. Türkan   +4 more
semanticscholar   +1 more source

Comparing enzyme activity modifier equations through the development of global data fitting templates in Excel [PDF]

open access: yesPeerJ, 2018
The classical way of defining enzyme inhibition has obscured the distinction between inhibitory effect and the inhibitor binding constant. This article examines the relationship between the simple binding curve used to define biomolecular interactions ...
Ryan Walsh
doaj   +2 more sources

Small molecule inhibition of METTL3 as a strategy against myeloid leukaemia

open access: yesNature, 2021
N6-methyladenosine (m6A) is an abundant internal RNA modification1,2 that is catalysed predominantly by the METTL3–METTL14 methyltransferase complex3,4.
E. Yankova   +24 more
semanticscholar   +1 more source

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