Results 41 to 50 of about 6,711,495 (336)

Legume lipoxygenase: Strategies for application in food industry

Legume Science, 2020
Lipoxygenase (LOX) is a widely distributed enzyme in plant and animal cells. It catalyzes the oxidation of polyunsaturated fatty acid into fatty acid hydroperoxides.
Yuan Shi, Ronit Mandal, Anika Singh, Anubhav Pratap Singh   +3 more
doaj   +1 more source

Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]

Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس, پناهپور, حمداله   +1 more
core   +1 more source

Inhibition studies of the protozoan α-carbonic anhydrase from Trypanosoma cruzi with phenols

, 2022
The α-class carbonic anhydrase (CA, EC 4.2.1.1) from the protozoan pathogen Trypanosoma cruzi, TcCA, was investigated earlier for its inhibition with anions, sulphonamides, thiols and hydroxamates, well-known classes of CA inhibitors (CAIs).
Bonardi, Alessandro, Parkkila, Seppo, Supuran, Claudiu T.   +2 more
core   +1 more source

Advances in Enzyme-Based Biosensors for Pesticide Detection

Biosensors, 2018
The intensive use of toxic and remanent pesticides in agriculture has prompted research into novel performant, yet cost-effective and fast analytical tools to control the pesticide residue levels in the environment and food.
Bogdan Bucur, Florentina-Daniela Munteanu, Jean-Louis Marty, Alina Vasilescu   +3 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Inhibition Of Bovine Kidney Low Molecular Mass Phosphotyrosine Protein Phosphatase By Uric Acid.

, 2015
Uric acid inhibited 50% of the activity of bovine kidney low molecular mass phosphotyrosine protein phosphatase at concentrations of 1.0, 0.4, 1.3, and 0.2 mM, respectively for p-nitrophenyl phosphate (p-NPP), flavine mononucleotide, beta-naphthyl ...
Ferreira, Carmen Verissima, Volpe, Pedro Luiz Onofre, Da Silva, Cinthia Celestino, Aoyama, Hiroshi, Granjeiro, Paulo Afonso, Granjeiro, José Mauro, Taga, Eulázio Mikio   +6 more
core   +2 more sources

ANTI-DIABETIC POTENTIAL OF PEPTIDE FROM P. NIRURI REVEALS THROUGH CARBOHYDRATE HYDROLYZING ENZYME INHIBITION ASSAY [PDF]

Science Heritage Journal, 2019
Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-
Noor Hasniza Md Zin, Ainul Mardhiah Mohd Nail   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Exploring of some benzoquinone derivatives impact on Acetylcholinesterase enzyme activity

German Journal of Pharmaceuticals and Biomaterials
The discovery of acetylcholinesterase inhibitors is important for the treatment of Alzheimer's disease, which is the most common type of dementia. Due to the side effects of commonly used acetylcholinesterase inhibitors, studies aimed at discovering new
Hatice Duran
doaj   +3 more sources