Results 41 to 50 of about 783,012 (204)

Inhibitory antibodies designed for matrix metalloproteinase modulation [PDF]

, 2019
The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Fischer, Thomas, Riedl, Rainer
core   +1 more source

Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities

Pharmacognosy Research, 2013
To date, many findings reveal that most of the modern drugs have the ability to interact with herbal drugs.This study was conducted to determine the inhibitory effects of mitragynine on cytochrome P450 2C9, 2D6 and 3A4 activities.The in vitro study was conducted using a high-throughput luminescence assay.Statistical analysis was conducted using one-way
Hanapi, N. A., Ismail, S., Mansor, S. M.
openaire   +3 more sources

Recent Advances in the Biological Activity of s-Triazine Core Compounds

Pharmaceuticals, 2022
An effective strategy for successful chemotherapy relies on creating compounds with high selectivity against cancer cells compared to normal cells and relatively low cytotoxicity. One such approach is the discovery of critical points in cancer cells, i.e.
Dawid Maliszewski, Danuta Drozdowska
doaj   +1 more source

Inhibitory activities of baicalin against renin and angiotensin-converting enzyme

Pharmaceutical Biology, 2011
Baicalin has been characterized as the active compound and quality control marker in Scutellaria baicalensis Georgi, traditionally used as a hypotensive herb.To investigate the inhibitory activities of baicalin against renin and angiotensin-I converting enzyme (ACE) and their molecule mechanism of interactions.The fluorescence method using renin ...
Y F, Deng, R E, Aluko, Q, Jin, Y, Zhang, L J, Yuan   +4 more
openaire   +2 more sources

Angiotensin-I-Converting Enzyme Inhibitory Activity and Antioxidant Properties of Cryptides Derived from Natural Actomyosin of Catla catla Using Papain

Journal of Food Quality, 2018
Natural actomyosin (NAM) from the freshwater fish Catla catla was extracted and hydrolyzed using papain enzyme at different enzyme-to-substrate ratios (0.5%, 1.0%, 2.0%, 5.0%, and 10%) to obtain the cryptides with different degrees of hydrolysis (DH ...
Krishnamoorthy Elavarasan, Bangalore Aswathnarayan Shamasundar   +1 more
doaj   +1 more source

Investigation of Antioxidant, Hypoglycemic and Anti-Obesity Effects of Euphorbia Resinifera L.

Journal of Pharmacopuncture, 2022
Objectives: The aim of this work is to evaluate the in vitro antioxidant, hypoglycemic, and antiobesity effects of Euphorbia resinifera extracts and investigate the phenolic constituents and the toxicity of these extracts.Methods : Phytochemical ...
Kaoutar Benrahou, Otman El Guourrami, Hanae Naceiri Mrabti, Yahia Cherrah, My El Abbes Faouzi   +4 more
doaj   +1 more source

Identification of ACE-inhibitory peptides from Phaseolus vulgaris after in vitro gastrointestinal digestion [PDF]

, 2015
The objective of this study was to identify the angiotensin I-converting enzyme (ACE)-inhibitory peptides released from thermally treated Phaseolus vulgaris (pinto) whole beans after in vitro gastrointestinal digestion. The degree of hydrolysis increased
Bellesia, Andrea, Conte, Angela, Martini, Serena, Tagliazucchi, Davide   +3 more
core   +1 more source

Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay

Molecules, 2017
Neuraminidase is a key enzyme in the life cycle of influenza viruses and is present in some bacterial pathogens. We here assess the inhibitory potency of plant tannins versus clinically used inhibitors on both a viral and a bacterial model neuraminidase ...
Stefanie Quosdorf, Anja Schuetz, Herbert Kolodziej   +2 more
doaj   +1 more source

Production of Angiotensin Converting Enzyme Inhibitory Peptides from Red Tilapia Protein Hydrolysates [PDF]

, 2010
Fish proteins are considered as valuable nutrient and a good source of many bioactive peptides such as angiotensin converting enzyme (ACE) inhibitory peptides. Very few reports are available on the ACE inhibitory peptides in freshwater fish hydrolysates.
Shamloo, Maryam
core  

Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]

, 2015
Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa, Florêncio Nogueira, Fouzi Mouffouk, Hugo Pereira, José Manuel, João Varela, Khalid M. Abu-salah, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Nuno Da Rosa Neng, Radhouan Ben-hamadou, Salman A. Alrokayan, The Red Sea   +14 more
core   +4 more sources