Results 81 to 90 of about 783,012 (204)

ATP mediates both activation and inhibition of K(ATP) channel activity via cAMP-dependent protein kinase in insulin-secreting cell lines. [PDF]

, 1989
The single-channel recording technique was employed to investigate the mechanism conferring ATP sensitivity to a metabolite-sensitive K channel in insulin-secreting cells.
Ciani, S, Eddlestone, GT, Ribalet, B
core  

Multifaceted Biological Activity of Rutin, Quercetin, and Quercetin’s Glucosides

Molecules
In this study, the ranking of the multifaceted activity of rutin (Ru), quercetin (Q), and quercetin’s glucosides (Q3G, Q4′G and Q3,4′G) was addressed.
Danuta Zielińska, Małgorzata Starowicz, Małgorzata Wronkowska, Henryk Zieliński   +3 more
doaj   +1 more source

Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity [PDF]

, 2019
A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA)
Alcaro, Stefano, Bagetta, Donatella, Carradori, Simone, Chimenti, Paola, Ferrante, Claudio, Guglielmi, Paolo, Leone, Sheila, Ortuso, Francesco, Petzer, Anél, Petzer, Jacobus P, Recinella, Lucia, Rotondi, Giulia, Secci, Daniela, Zengin, Gokhan   +13 more
core   +1 more source

Inhibitory Activities of 2-Pyridinecarboxylic Acid Analogs on Phytogrowth and Enzymes.

Biological and Pharmaceutical Bulletin, 1999
Five 2-pyridinecarboxylic acid-related compounds (1, 2 and 5-7) showed germination inhibition against the seed of Brassica campestris L. subsp. rapa HOOK fil et ANDERS at a concentration of 5.0 x 10(-4) M. These compounds also demonstrated inhibitory activity on the growth of the root of this plant at a concentration of 3.0 x 10(-4) M; among these ...
Y, Sakagami, H, Tsujibo, Y, Hirai, T, Yamada, A, Numata, Y, Inamori   +5 more
openaire   +3 more sources

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis. [PDF]

, 2016
The invasion-promoting MT1-MMP is a cell surface-associated collagenase with a plethora of critical cellular functions. There is a consensus that MT1-MMP is a key protease in aberrant pericellular proteolysis in migrating cancer cells and, accordingly, a
Cieplak, Piotr, Ge, Xin, Nam, Dong Hyun, Remacle, Albert G, Shiryaev, Sergey A, Strongin, Alex Y   +5 more
core   +1 more source

Evaluation of Enzyme Inhibitory Effects and Phytochemical Analysis by LC-Q-ToF MS of Some Polygonum L. Species Growing in Türkiye

Journal of Agricultural Sciences
Polygonum species have strong biological activity due to their important bioactive components. Polygonum species have been studied for enzyme inhibition activity, wound healing, anti-inflammatory, antibacterial, antiviral, antioxidant effects ...
Tuğsen Büyükyıldırım, Fatma Sezer Şenol Deniz, Osman Tugay, Ayhan İbrahim Aysal, İlkay Erdoğan Orhan   +4 more
doaj   +1 more source

Biscuits from Fermented Roasted Buckwheat Flour - Phenolics Profile and Bioaccessible Angiotensin Converting Enzyme Inhibitory Activity

Acta Universitatis Cibiniensis. Series E: Food Technology, 2020
The bioaccessible angiotensin converting enzyme (ACE) inhibitory activity of biscuits formulated from roasted common buckwheat flour after fermentation by select bacteria was studied.
Wronkowska Małgorzata, Honke Joanna, Zieliński Henryk, Wiczkowski Wiesław   +3 more
doaj   +1 more source

Estudio del efecto inhibitorio de extractos de Salvia scutellarioides sobre la actividad de la enzima convertidora de angiotensina

Universitas Scientiarum, 2009
Study of the inhibitory effect of Salvia scutellarioides extracts on the activity of the angiotensin-converting enzyme. Objective. Toidentify groups of secondary metabolites of Salvia scutellarioides present in the fraction with the greatest inhibitory ...
Gina Méndez-Callejas, Antonio Guzmán-Avendaño, Erica Pachón-Gómez, Raúl Arenas-Carvajal   +3 more
doaj  

Unbalance between Excitation and Inhibition in Phenylketonuria, a Genetic Metabolic Disease Associated with Autism [PDF]

, 2017
Phenylketonuria (PKU) is the most common genetic metabolic disease with a well-documented association with autism spectrum disorders. It is characterized by the deficiency of the phenylalanine hydroxylase activity, causing plasmatic hyperphenylalaninemia
Andolina, Diego, Colamartino, Marco, DE ANGELIS, Federica, DE JACO, Antonella, Favaloro, FLORES LIETTA, Fiori, Elena, Mango, Dalila, Nistico', ROBERT GIOVANNI, Pascucci, Tiziana   +8 more
core   +2 more sources

Optimization of the extraction process of ACE inhibitory peptides from distillery waste and their antioxidant activity

Shipin yu jixie
ObjectiveThis study aimed to handle distillery waste effectively, research and develop high-value components within distillery waste, and explore its potential application approaches.MethodsProteins were extracted from distillery waste throuth the ...
YAO Mingcai, LI Feifeng, LUO Guang, DONG Liang   +3 more
doaj   +1 more source