Results 21 to 30 of about 355,555 (310)
Microbial Cell Factories, 2021 Background The aryltetralin lignan (−)−podophyllotoxin is a potent antiviral and anti-neoplastic compound that is mainly found in Podophyllum plant species. Over the years, the commercial demand for this compound rose notably because of the high clinical
Davide Decembrino +4 more
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A minimal biochemical route towards de novo formation of synthetic phospholipid membranes. [PDF]
, 2019 All living cells consist of membrane compartments, which are mainly composed of phospholipids. Phospholipid synthesis is catalyzed by membrane-bound enzymes, which themselves require pre-existing membranes for function.
Bhattacharya, Ahanjit +3 more
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Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases
mBio, 2015 Vancomycin resistance in Gram-positive bacteria results from the replacement of the d-alanyl–d-alanine target of peptidoglycan precursors with d-alanyl–d-lactate or d-alanyl–d-serine (d-Ala-d-Ser), to which vancomycin has low binding affinity.
Djalal Meziane-Cherif +5 more
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Redox Biology, 2021 The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors.
Jeffrey M. Stolwijk +6 more
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Biochemistry of Human Axilla Malodor and Chemistry of Deodorant Ingredients
CHIMIA, 2007 Key human axilla malodorants are hexenoic acid (3) and 3-hydroxy-3-methyl-hexanoic acid (5), accompanied by some 25 structurally related hydroxyalkanoic acids and alkenoic acids.
Markus Gautschi +2 more
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Enzymic Cross-Linkage of Monomeric Extensin Precursors in Vitro [PDF]
Plant Physiology, 1988 Rapidly growing tomato (Lycopersicon esculentum) cell suspension cultures contain transiently high levels of cell surface, salt-elutable, monomeric precursors to the covalently cross-linked extensin network of the primary cell wall. Thus, we purified a highly soluble monomeric extensin substrate from rapidly growing cells, and devised a soluble in ...
D S, Everdeen +6 more
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From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis. [PDF]
, 2011 In most eubacteria, apicomplexans, and most plants, including the causal agents for diseases such as malaria, leprosy, and tuberculosis, the methylerythritol phosphate pathway is the route for the biosynthesis of the C(5) precursors to the essential ...
de Oliveira, César Augusto F +3 more
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Aromatase Activity and Bone Loss in Men
Journal of Osteoporosis, 2011 Aromatase is a specific component of the cytochrome P450 enzyme system responsible for the transformation of androgen precursors into estrogens. This enzyme is encoded by the CYP19A1 gene located at chromosome 15q21.2, that is, expressed in ovary and ...
Daniela Merlotti +3 more
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The role of human Dicer-dsRBD in processing small regulatory RNAs. [PDF]
PLoS ONE, 2012 One of the most exciting recent developments in RNA biology has been the discovery of small non-coding RNAs that affect gene expression through the RNA interference (RNAi) mechanism.
Christopher Wostenberg +6 more
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Biocatalytic self-assembly cascades [PDF]
, 2017 The properties of supramolecular materials are dictated by both kinetic and thermodynamic aspects, providing opportunities to dynamically regulate morphology and function.
Abul-Haija +46 more
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