Results 31 to 40 of about 1,224,230 (307)

Studies on the formation and synthetic mechanism of related substance G in potassium clavulanate production

Brazilian Journal of Pharmaceutical Sciences, 2015
The objective of this study was to investigate the formation and synthetic mechanism of related substance G in potassium clavulanate production. The impurity in the potassium clavulanate final product, with a retention time of 13.5 min, was confirmed as ...
Xiaoqing Jin, Guangxiang Cao, Xiaoxiao Zhang, Yuguo Chen, Liang Wang, Chuanqing Zhong   +5 more
doaj   +1 more source

Trimethylamine N-Oxide as a Potential Biomarker for Cardiovascular Disease: Its Association with Dietary Sources of Trimethylamine N-Oxide and Microbiota

Eurasian Journal of Medicine, 2023
Trimethylamine N-oxide (TMAO), the oxidized form of trimethylamine (TMA), was previously thought to be a waste product but is now considered an important risk factor for cardiovascular disease (CVD) and its comorbidities. Foods or supplements containing
Yasemin Karaagac
doaj   +1 more source

Enzymic Cross-Linkage of Monomeric Extensin Precursors in Vitro [PDF]

Plant Physiology, 1988
Rapidly growing tomato (Lycopersicon esculentum) cell suspension cultures contain transiently high levels of cell surface, salt-elutable, monomeric precursors to the covalently cross-linked extensin network of the primary cell wall. Thus, we purified a highly soluble monomeric extensin substrate from rapidly growing cells, and devised a soluble in ...
D S, Everdeen, S, Kiefer, J J, Willard, E P, Muldoon, P M, Dey, X B, Li, D T, Lamport   +6 more
openaire   +2 more sources

MACiE: a database of enzyme reaction mechanisms. [PDF]

, 2005
SUMMARY: MACiE (mechanism, annotation and classification in enzymes) is a publicly available web-based database, held in CMLReact (an XML application), that aims to help our understanding of the evolution of enzyme catalytic mechanisms and also to create
Gemma L. Holliday, Bartlett, G J, Noel M. O'Boyle, Janet M. Thornton, O'Boyle, N M, Peter Murray-Rust, John B. O. Mitchell, Holliday, G L, Almonacid, D E, Murray-Rust, P, Daniel E. Almonacid, Thornton, J M, Mitchell, John Blayney Owen, Gail J. Bartlett   +13 more
core   +2 more sources

Immobilization on biomimetic silica nanoparticles as a highly effective strategy for the stabilization of Issatchenkia orientalis β-glucosidase in wine conditions

Results in Chemistry, 2023
β-Glucosidases (BGLs) are key enzymes for the hydrolysis of glycosidic aroma precursors of wines. However, BGLs produced by oenological yeasts are often inactive or unstable at typical wine pH values.
Stefani de Ovalle, Beatriz M. Brena, Paula González-Pombo   +2 more
doaj   +1 more source

Substrate- and species-specific processing enzymes for chloroplast precursor proteins [PDF]

Biochemical Journal, 1994
Using different precursors of chloroplast proteins and stromal extracts from both Chlamydomonas reinhardii and pea chloroplasts, we analysed the specificity of stroma-localized processing peptidases. By gel filtration of a stromal extract from isolated Chlamydomonas chloroplasts, fractions could be separated containing enzymic activities for processing
Su Q, Boschetti A
openaire   +3 more sources

Astroenzymology – the environmental limits of enzyme activity [PDF]

, 2003
Using organisms from extreme terrestrial environments as models for extraterrestrial life may lead us to underestimate the range of environments that life may inhabit.
Daniel, Roy M., Roy Daniel
core   +1 more source

Prothrombin concentrations in middle-aged men and women – stability over time and correlations with cardiovascular risk factors

Thrombosis Update
Background: Prothrombin is a vitamin K-dependent glycoprotein synthesized in the liver and circulating in blood as an inactive zymogen. The corresponding activated thrombin enzyme is a central player in hemostasis and thrombosis.
Bengt Zöller, Mark Jonas Haastrup, Niels Tækker Foged, Gunnar Engström   +3 more
doaj   +1 more source

Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls [PDF]

, 2007
Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Tenhaken, Raimund, Klinghammer, Michaela
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source