Results 21 to 30 of about 1,224,230 (307)

Biochemistry of Human Axilla Malodor and Chemistry of Deodorant Ingredients

open access: yesCHIMIA, 2007
Key human axilla malodorants are hexenoic acid (3) and 3-hydroxy-3-methyl-hexanoic acid (5), accompanied by some 25 structurally related hydroxyalkanoic acids and alkenoic acids.
Markus Gautschi   +2 more
doaj   +1 more source

Protein-protein interactions of human somatic angiotensin-converting enzyme [PDF]

open access: yes, 2011
In this study, novel disulphide bridges were engineered into the linker region of ACE [Angiotensin-converting enzyme] in an attempt to limit inter-domain movement, thereby producing a candidate for crystallisation and to determine the effect of these ...
Gordon, Kerry
core   +1 more source

Aromatase Activity and Bone Loss in Men

open access: yesJournal of Osteoporosis, 2011
Aromatase is a specific component of the cytochrome P450 enzyme system responsible for the transformation of androgen precursors into estrogens. This enzyme is encoded by the CYP19A1 gene located at chromosome 15q21.2, that is, expressed in ovary and ...
Daniela Merlotti   +3 more
doaj   +1 more source

The role of human Dicer-dsRBD in processing small regulatory RNAs. [PDF]

open access: yesPLoS ONE, 2012
One of the most exciting recent developments in RNA biology has been the discovery of small non-coding RNAs that affect gene expression through the RNA interference (RNAi) mechanism.
Christopher Wostenberg   +6 more
doaj   +1 more source

Enzyme-triggered Radical Reactions: Another Approach For Tin-free Radical Chemistry

open access: yesCHIMIA, 2012
The system laccase/mediator/dioxygen is able to trigger radical reactions with radical precursors which are not natural substrates of this enzyme.
Ibrahima Cissokho   +5 more
doaj   +1 more source

Enzymic formation of esters of methyl sterol precursors of cholesterol

open access: yesJournal of Lipid Research, 1971
For investigation of the reactions of cholesterol biosynthesis, a number of workers use the 10,000 g supernatant fraction (or similar preparations) obtained from cell-free homogenates of rat liver. We have found that esters of methyl sterol biosynthetic intermediates are formed by this crude source of enzymes. Esters of C(30)-, C(29)-, C(28)-, and C(27)
D.R. BRADY, J.L. GAYLOR
openaire   +3 more sources

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

open access: yesNature Communications, 2016
Autophagy must be tightly controlled at each step of the process. Here the authors show that HS1BP3 binds phosphatidic acid (PA) at autophagosome precursors and negatively regulates autophagosome formation by modulating the activity and localization of ...
Petter Holland   +15 more
doaj   +1 more source

Melatonin, its precursors, and synthesizing enzyme activities in the human ovary [PDF]

open access: yesMolecular Human Reproduction, 1999
The presence of melatonin (N-acetyl-5-methoxytryptamine) and its precursors, serotonin (5-hydroxytryptamine) and N-acetylserotonin, was demonstrated in extracts of human ovary using reverse-phase high-performance liquid chromatography coupled with fluorometric detection.
M T, Itoh   +4 more
openaire   +2 more sources

Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer [PDF]

open access: yesJournal of Biological Chemistry, 1999
Human platelet heparanase has been purified to homogeneity and shown to consist of two, non-covalently associated polypeptide chains of molecular masses 50 and 8 kDa. Protein sequencing provided the basis for determination of the full-length cDNA for this novel protein. Based upon this information and results from protein analysis and mass spectrometry,
M B, Fairbanks   +10 more
openaire   +2 more sources

Structure-activity relationships of synthetic analogs of jasmonic acid and coronatine on induction of benzo[c]phenanthridine alkaloid accumulation in Eschscholzia californica cell cultures [PDF]

open access: yes, 2000
A facile test system based on the accumulation of benzo[c]phenanthridine alkaloids in Eschscholzia californica cell suspension culture (an indicator of defense gene activation) has been used to analyze a series of synthetic compounds for elicitor-like ...
Blechert, S.   +4 more
core   +1 more source

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