Results 71 to 80 of about 978,452 (311)

A novel enzymatic approach to nanocrystalline cellulose preparation [PDF]

, 2018
In this work, conditions for an enzymatic pretreatment prior to NCC isolation from cotton linter were assessed. Different cellulase doses and reaction times were studied within an experimental design and NCC were obtained. At optimal enzymatic conditions
Beltramino, Facundo, Roncero Vivero, María Blanca, Valls Vidal, Cristina, Vidal Lluciá, Teresa   +3 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Considerations when Measuring Biocatalyst Performance

Molecules, 2019
As biocatalysis matures, it becomes increasingly important to establish methods with which to measure biocatalyst performance. Such measurements are important to assess immobilization strategies, different operating modes, and reactor configurations ...
Mafalda Dias Gomes, John M. Woodley
doaj   +1 more source

Activity and Process Stability of Purified Green Pepper (Capsicum annuum) Pectin Methylesterase [PDF]

, 2004
Pectin methylesterase (PME) from green bell peppers (Capsicum annuum) was extracted and purified by affinity chromatography on a CNBr-Sepharose-PMEI column. A single protein peak with pectin methylesterase activity was observed.
Alonso J., Alonso J., Anthon G. E., Castaldo D., Crelier S., Denès J.-M., Doesburg J., Eagerman B. A., Fachin D., Giovane A., Gross K. C., Heuskeshoven J., Indrawati, Indrawati, Jen J. J., Korner B., Laats M. M., Lee Y. S., Lin T. P., Ly-Nguyen B., Ly-Nguyen B., Markovič O., Pressey R., Puri A., Ramesh M. N., Rexová-Benková L., Sethu K. M. P., Seyderhelm I., Seymour T. A., Van den Broeck I., Van den Broeck I., Van den Broeck I., Versteeg C., Wicker L., Yemenicioǧlu A.   +34 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Support Materials of Organic and Inorganic Origin as Platforms for Horseradish Peroxidase Immobilization: Comparison Study for High Stability and Activity Recovery

Molecules
In the presented study, a variety of hybrid and single nanomaterials of various origins were tested as novel platforms for horseradish peroxidase immobilization.
Muhammad Bilal, Oliwia Degorska, Daria Szada, Agnieszka Rybarczyk, Agata Zdarta, Michal Kaplon, Jakub Zdarta, Teofil Jesionowski   +7 more
doaj   +1 more source

Fully Integrated Biochip Platforms for Advanced Healthcare [PDF]

, 2012
Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers.
Baj-Rossi, Camilla, Burleson, Wayne, Carrara, Sandro, Cavallini, Andrea, de Beeck, Maaike Op, Dehollain, Catherine, Ghoreishizadeh, Sara, Guiseppi-Elie, Anthony, Micheli, Giovanni De, Moussy, Francis Gabriel, Olivo, Jacopo, Taurino, Irene   +11 more
core   +5 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Enhancing the Catalytic Performance of β-Mannanase via Polyvinyl Alcohol Immobilization and Genipin Modification

Molecules
This study reports the immobilization of β-mannanase from Aspergillus niger—either unmodified or genipin-modified—within polyvinyl alcohol hydrogels (PVA@mannanase and PVA@mannanase-Gen) for the enhanced production of mannooligosaccharides (MOSs).
Nazli Ece Varan Faki, Ali Toprak, Guzide Yucebilgic, Dilek Alagöz, Deniz Yildirim, Roberto Fernandez-Lafuente   +5 more
doaj   +1 more source

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M., Bethel, Christopher R., Bonomo, Robert A., Giannini, Estefanía, Klinke, Sebastian, Llarrull, Leticia Irene, Mojica, María F., Otero, Lisandro Horacio, Palacios, Antonela Rocio, Taracila, Magdalena A., Vila, Alejandro Jose   +10 more
core   +1 more source