Results 171 to 180 of about 2,250,147 (369)

Role of pretty nanoflowers as novel versatile analytical tools for sensing in biomedical and bioanalytical applications

Smart Medicine
In recent years, an encouraging breakthrough in the synthesis of immobilized enzymes in flower‐shaped called “organic‐inorganic hybrid nanoflowers (hNFs)” with greatly enhanced catalytic activity and stability were reported.
Seyma Dadi, Ismail Ocsoy
doaj   +1 more source

Chemically stabilized subtilisins in peptide synthesis [PDF]

, 2008
We have stabilized alcalaseTM and subtilisin Carlsberg (SC) against heat by chemical modification with ethylene glycol bis-succinimidyl succinate (EGNHS), a procedure not previously reported for subtilisins.
Colleary, Sandra, Ó Fágáin, Ciarán
core  

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

UniZyme: A Unified Protein Cleavage Site Predictor Enhanced with Enzyme Active-Site Knowledge [PDF]

arXiv
Enzyme-catalyzed protein cleavage is essential for many biological functions. Accurate prediction of cleavage sites can facilitate various applications such as drug development, enzyme design, and a deeper understanding of biological mechanisms. However, most existing models are restricted to an individual enzyme, which neglects shared knowledge of ...
arxiv  

Effective and Practical Stereoselective Synthesis of Nutlins Precursors by Immobilization of Privileged Chiral Mono‐Amidine Catalyst

Advanced Synthesis &Catalysis, EarlyView.
Abstract A strategy for the immobilization of Johnston's Mono(AMidine) catalyst (MAM) onto polystyrene, silica and hybrid silica‐polystyrene nanoparticles is presented. The catalyst activity was evaluated in the stereoselective aza‐Henry reaction leading to the pivotal β‐amino nitroalkane precursors of the anti‐cancer agents Nutlins (with Nutlin‐3a as ...
Sofia Toldo, Lorenzo Poletti, Graziano Di Carmine, Olga Bortolini, Carmela De Risi, Simona Felletti, Greta Compagnin, Alessandro Massi, Daniele Ragno   +8 more
wiley   +1 more source

Continuous Flow Technology Enabling Photochemistry

Advanced Synthesis &Catalysis, EarlyView.
Abstract The merger of continuous flow technology and modern photochemistry has enabled countless applications showcasing new opportunities for chemical synthesis demonstrating improvements in selectivity, safety, sustainability and scalability. This focused review aims to highlight a selection of recently published case studies from academic and ...
Ruairi Crawford, Marcus Baumann
wiley   +1 more source

Functional Molecule‐Integrated Nano‐Interfaces for Detection of Extracellular Vesicles

Advanced Sensor Research, EarlyView.
Functional molecule‐integrated nano‐interfaces for detection of extracellular vesicles prepared via template polymerization using multifunctional polymer–silica nanoparticle complex as a template followed by post‐functionalization modification are demonstrated.
Hirobumi Sunayama, Yuya Matsui, Toshifumi Takeuchi   +2 more
wiley   +1 more source

Survey of CELSS Concepts and Preliminary Research in Japan [PDF]

, 1985
Agricultural and other experiments relating to the development of a controlled ecological life support system (CELSS) were proposed. The engineering feasibility of each proposal was investigated by a CELSS experiment concept met study group.
Nitta, K., Ohya, H., Oshima, T.
core   +1 more source

Methods of Enzyme Immobilization

, 2016
Enzyme immobilization is a technique specifically designed to restrict the freedom of movement of an enzyme.Immobilization of enzymes is a common practice, mainly in order to minimize enzyme costs on the process economics bymaking it possible to reuse the enzyme many times and also minimize the operation cost as the immobilization techniquemay be ...
Hassan Mohamed E, Tamer Tamer M, Omer Ahmed M   +2 more
openaire   +1 more source

Modulating Signal Generation in Aptamer‐Based CNT‐FET Biosensors by Controlling the Functionalization Route

Advanced Sensor Research, EarlyView.
The impact of different assembly strategies is discussed on the performance of nanoscale aptamer‐based SWCNT‐FET biosensors. By combining electrical and optical characterization, this is revealed that how aptamer conformation affects local electrostatic changes within the Debye length, leading to distinct sensor responses.
Haosen Miao, Gririraj Manoharan, Ahran Lim, Peter Mirau, Jorge L. Chávez, Chang‐Seuk Lee, Matteo Palma   +6 more
wiley   +1 more source