Results 221 to 230 of about 2,250,147 (369)

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

Affinity Electrophoresis of Proteins for Determination of Ligand Affinity and Exploration of Binding Sites. [PDF]

Int J Mol Sci
Masson P, Pashirova T.
europepmc   +1 more source

Recent advances in immobilized enzymes on nanocarriers

, 2016
Shi-Lin Cao, Pei Xu, Yongzheng Ma, Xiaoxiao Yao, Yuan Yao, Min-hua Zong, Xuehui Li, Wenyong Lou   +7 more
semanticscholar   +1 more source

Increasing the activity of immobilized enzymes with nanoparticle conjugation.

Current Opinion in Biotechnology, 2015
Shaowei Ding, Allison A. Cargill, Igor L. Medintz, J. Claussen   +3 more
semanticscholar   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, EarlyView.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

Carboxylated nanocellulose from quinoa husk for enhanced protease immobilization and stability of protease in biotechnological applications. [PDF]

Sci Rep
Ariaeenejad S, Motamedi E.
europepmc   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

Biofunctionalization of Magneto-Plasmonic Fe₃O₄@SiO₂-NH₂-Au Heterostructures with the Cellulase from <i>Trichoderma reesei</i>. [PDF]

Molecules
Tomaszewska A, Kulpa-Greszta M, Hryców O, Niemczyk K, Wojnarowska-Nowak R, Broda D, Pazik R.   +6 more
europepmc   +1 more source

A New Strategy to Functionalize Exosomes via Enzymatic Engineering of Surface Glycans and its Application to Profile Exosomal Glycans and Endocytosis

Advanced Science, EarlyView.
Enzymatic introduction of azido‐sialic acid residues to the glycans on exosomes enables a new and efficient approach for exosomal functionalization with various probes, including biotin and fluorophores, by biocompatible click chemistry, thereby facilitating detailed investigations of exosomes, such as their glycan profiles, cellular uptake, etc., and ...
Sayan Kundu, Jiatong Guo, Md. Shamiul Islam, Rajendra Rohokale, Mohit Jaiswal, Zhongwu Guo   +5 more
wiley   +1 more source

Crystallization-Assisted Asymmetric Synthesis of Enantiopure Amines Using Membrane-Immobilized Transaminase. [PDF]

Chem Bio Eng
Meersseman Arango H, Bachus N, Nguyen XDL, Bredun B, Luis P, Leyssens T, Roura Padrosa D, Paradisi F, Debecker DP.   +8 more
europepmc   +1 more source