Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie+10 more
wiley +1 more source
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang+10 more
wiley +1 more source
Designed Reactive Natural Deep Eutectic Solvents for Lipase-Catalyzed Esterification. [PDF]
Buzatu AR+8 more
europepmc +1 more source
Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu+6 more
wiley +1 more source
Enhancement of Lycopene Biosynthesis Using Self-Assembled Multi-Enzymic Protein Cages. [PDF]
Zhou Y+5 more
europepmc +1 more source
Multifunctional Conductive Nanofibers for Self‐Powered Glucose Biosensors
This work develops a novel self‐powered glucose biosensor using polycaprolactone/polypyrrole/graphene oxide (PCL/PPy/GO) nanofibers integrated with a triboelectric nanogenerator. The system achieves high glucose detection sensitivity and generates 63 V from motion, combining robust mechanical strength with eco‐friendly energy harvesting.
Seda Gungordu Er+7 more
wiley +1 more source
Immobilized Nucleoside 2'-Deoxyribosyltransferases from Extremophiles for Nucleoside Biocatalysis. [PDF]
Antonio Hernández Martínez S+4 more
europepmc +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao+9 more
wiley +1 more source
Exploiting Silica-Binding and Silica-Forming Proteins as Versatile Tools for One-Step Enzyme Immobilization on Siliceous Materials. [PDF]
Lim GT, Jo BH.
europepmc +1 more source
Multiparametric determination of genes and their point mutations for identification of beta-lactamases [PDF]
A. A. Medeiros+127 more
core +1 more source