Results 241 to 250 of about 2,250,147 (369)

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

Preparation and Biochemical Characterization of <i>Penicillium crustosum</i> Thom P22 Lipase Immobilization Using Adsorption, Encapsulation, and Adsorption-Encapsulation Approaches. [PDF]

Molecules
Hasnaoui I, Mechri S, Dab A, Bentouhami NE, Abouloifa H, Bellaouchi R, Allala F, Saalaoui E, Jaouadi B, Noiriel A, Asehraou A, Abousalham A.   +11 more
europepmc   +1 more source

DNA Molecular Computing with Weighted Signal Amplification for Cancer miRNA Biomarker Diagnostics

Advanced Science, EarlyView.
A molecular computing approach is presented with weighted signal amplification. Polymerase‐mediated strand displacement is employed to assign weights to target miRNAs, reflecting the miRNAs’ diagnostic values, followed by amplification of the weighted signals using localized DNA catalytic hairpin assembly.
Hongyang Zhao, Yumin Yan, Linghao Zhang, Xin Li, Lan Jia, Liang Ma, Xin Su   +6 more
wiley   +1 more source

Rapid detection of hydrogen peroxide and nitrite in adulterated cow milk using enzymatic and nonenzymatic methods on a reusable platform. [PDF]

RSC Adv
Bharwani H, Kapur S, Palani SG.
europepmc   +1 more source

Ruthenium Single‐Atom Nanozyme Driven Sonosensitizer with Oxygen Vacancies Enhances Electron–Hole Separation Efficacy and Remodels Tumor Microenvironment for Sonodynamic‐Amplified Ferroptosis

Advanced Science, EarlyView.
An atomic‐level engineered ruthenium single‐atom nanozyme is fabricated that features sufficient oxygen vacancies and electron and hole separation efficiency, which enhances response to the sono‐suppressive tumor microenvironment and induces tumor ferroptosis.
Yang Zhu, Dengliang Wang, Chengzhong Du, Tiantian Wu, Penghui Wei, Hongjia Zheng, Guanting Li, ShunZhe Zheng, Lichao Su, Lingjun Yan, Yongrui Hu, Huimin Wang, Lisen Lin, Chenyu Ding, Xiaoyuan Chen   +14 more
wiley   +1 more source

Immobilization of purified pectinase from Aspergillus nidulans on chitosan and alginate beads for biotechnological applications. [PDF]

Microb Cell Fact
El-Shora HM, Abo-Elmaaty SA, El-Sayyad GS, Al-Bishri WM, El-Batal AI, Hassan MG.   +5 more
europepmc   +1 more source

Reversible High‐Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation

Advanced Science, EarlyView.
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi, Meijuan He, Hao Chen, Xuefei Wei, Liping Xiao, Xiaoqiang Shang, Yifeng Shi, Qi Wang, Lisha Yu, Jie Fan   +9 more
wiley   +1 more source

Biohybrid Nanosystem Fabricated with Marine Diatom <i>Thalassiosira pseudonana</i> for Uric Acid Detection. [PDF]

ACS Biomater Sci Eng
Yang X, Long S, Wang B, Chen J, Xiong Y, Ying M.   +5 more
europepmc   +1 more source

Enhanced the Trans‐Cleavage Activity of CRISPR‐Cas12a Using Metal‐Organic Frameworks as Stimulants for Efficient Electrochemical Sensing of Circulating Tumor DNA

Advanced Science, EarlyView.
This work designs manganese metal‐organic frameworks (Mn‐MOFs) co‐assembled with Cas12a/crRNA, enabling rapid release of Mn2⁺ under mild conditions. The MOFs‐induced proximity effect sustains Mn2⁺‐Cas12a/crRNA interactions, enhancing the trans‐cleavage activity of complex available to develop an electrochemical biosensor based on Mn‐MOFs‐enhanced ...
Shuai Wu, Yincheng Liu, Tianyu Zeng, Tianci Zhou, Yanting Sun, Ying Deng, Juan Zhang, Genxi Li, Yongmei Yin   +8 more
wiley   +1 more source

Biofuel Cells Based on Oxidoreductases and Electroactive Nanomaterials: Development and Characterization. [PDF]

Biosensors (Basel)
Demkiv O, Stasyuk N, Gayda G, Zakalska O, Gonchar M, Nisnevitch M.   +5 more
europepmc   +1 more source