Results 181 to 190 of about 1,930,061 (319)

<i>In vitro</i> Evaluation of the Digestive Tolerance of Water-Soluble Sodium β-(1→4)-Polyglucuronate. [PDF]

J Appl Glycosci (1999)
Sato I, Kawashima E, Isogai A.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Molecular dynamics simulations of temperature-dependent PET binding in PETase, ThermoPETase, and FAST-PETase. [PDF]

RSC Adv
Karaoli A, Mintis DG, Tzoupis H, Kiranoudis CT, Lynch I, Melagraki G, Afantitis A.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Going full circle: dynamic covalent enzyme immobilisation <i>via</i> visually trackable boronate esters. [PDF]

Chem Sci
Bojanov G, Swit J, Paradisi F.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics.

Analyst
Eenink BDG, Holstein JM, Heberlein M, Dilkaute C, Jose J, Hollfelder F, van Loo B, Bornberg-Bauer E, Kaminski TS, Lange A.   +9 more
europepmc   +1 more source

PHA synthase variant design using a conditional variational autoencoder. [PDF]

PLoS Comput Biol
Tenkanen T, Ylinen A, Jouhten P, Penttilä M, Castillo S.   +4 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

The Pyridoxal-5'-Phosphate-Dependent Enzymes of <i>Mycobacterium tuberculosis</i>. [PDF]

ACS Infect Dis
Peracchi A, Baker B.
europepmc   +1 more source