Results 81 to 90 of about 222,956 (401)
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
European Clinical Respiratory Journal, 2018 Background: Eosinophilic airway inflammation is common in asthma patients and appears to be associated with severe exacerbations and loss of asthma control.
Mika J. Mäkelä +4 more
doaj +1 more source
Frontiers in Pediatrics, 2021 The relationship between eosinophils/basophils and allergic sensitization is not clear in pediatric adenotonsillar hypertrophy (ATH). The objective of this study is to investigate the relationship between eosinophil/basophil counts and peripheral ...
Juanjuan Zou +7 more
doaj +1 more source
Eosinophil Granule Proteins: Form and Function
Journal of Biological Chemistry, 2014 Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to more recently identified immunomodulatory roles in shaping innate ...
K. Ravi Acharya, Steven J. Ackerman
semanticscholar +1 more source
Journal of Clinical Investigation, 2004 Eosinophils accumulate in high numbers in the lungs of asthmatic patients. These cells have the ability to induce tissue damage, a capacity that relates to their traditional role in host defense against parasitic worms. On the other hand, eosinophils produce growth factors associated with tissue repair and remodeling, notably TGF-beta1.
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
The transcription factor XBP1 is selectively required for eosinophil differentiation
Nature Immunology, 2015 The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in granulocyte maturation has remained unknown. Here we discovered an unexpectedly selective and absolute
Sarah E. Bettigole +6 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An +8 more
wiley +1 more source
Allergology International, 2004 Background: Adhesion molecules participate in an important part of inflammatory process in relation to the accumulation of inflammatory cells, such as eosinophils. The expression of adhesion molecules differs depending upon the cells and tissue.
Kazutoshi Yamaguchi +8 more
doaj +1 more source
Remission of Kimura disease with carotid hypervascularization after cyclosporine treatment [PDF]
, 2020 No abstract ...
Bartolazzi, Armando +7 more
core +2 more sources