Results 51 to 60 of about 189,176 (292)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Application of Raman Microspectroscopic and Raman imaging techniques for cell biological studies [PDF]

, 1995
Raman spectroscopy is being used to study biological molecules for some three decades now. Thanks to continuing advances in instrumentation more and more applications have become feasible in which molecules are studied in situ, and this has enabled Raman
Bakker Schut, T.C., Figdor, C.G., Grauw, C.J. de, Greve, J., Grond, M., Maraboeuf, F., Puppels, G.J., Sijtsema, N.M.   +7 more
core   +10 more sources

Unilateral orbital eosinophilic cellulitis (Wells syndrome)

Turkderm Turkish Archives of Dermatology and Venereology
Eosinophilic cellulitis, also known as Wells syndrome, is a rare inflammatory skin disorder of unknown etiology. The disease has no known racial or sexual predisposition. It usually affects adults, although it can also be observed in children. Typically,
İrem Nur Durusu Türkoğlu, Çağrı Turan, Çiğdem Özdemir, Yasin Sarıkaya, Özgür Eroğul   +4 more
doaj   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C Grayson   +6 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Evidence-based answers to clinical controversies in the management of severe asthma [PDF]

Exploration of Asthma & Allergy
Asthma is a chronic inflammatory airway disorder characterized by recurrent symptoms, airflow obstruction, and bronchial hyperresponsiveness. Approximately 5–10% of asthma cases are classified as severe, requiring high-dose inhaled corticosteroids (ICS ...
David El-Qutob, Martin Maillo
doaj   +1 more source

Highly Conductive and Stretchable Photothermal CuSe Fiber for Wearable Electronics and Implantable Drug Release Systems

Advanced Functional Materials, EarlyView.
The conductive and stretchable photothermal CuSe fiber is fabricated for versatile biomedical applications. This CuSe fiber functions as a reliable wearable strain sensor and heater due to its high conductivity, stretchability and photothermal efficiency.
Kukro Yoon, Yukye Lee, Sang Ki Rhee, Hyeonjoo Park, Kyowon Kang, Mingyu Sang, Byeonggwan Kim, Jung Seung Lee, Jaehong Lee, Taeyoon Lee   +9 more
wiley   +1 more source

Optimal Management of Allergic Fungal Rhinosinusitis

Journal of Asthma and Allergy, 2020
Gaurav Medikeri,1 Amin Javer2 1Medikeri’s Superspeciality ENT Center, Bangalore, India; 2Rhinology & Skull Base Surgery, St. Paul’s Sinus Center, Vancouver, BC, CanadaCorrespondence: Amin JaverSt.
Medikeri G, Javer A
doaj  

Two years follow-up of relapsing eosinophilic pneumonia with concomitant severe asthma successfully treated with benralizumab: A case report and brief review of the literature

Respiratory Medicine Case Reports, 2023
Relapsing eosinophilic pneumonia and severe eosinophilic asthma are rare and disabling diseases, which share common inflammatory backgrounds and often require long-term systemic steroid therapy.
G. Angeletti, M. Mazzolini, A. Rocca
doaj   +1 more source

Head and Neck Manifestations of Eosinophilic Granulomatosis with Polyangiitis: A Systematic Review. [PDF]

, 2016
OBJECTIVE: To conduct the first and only systematic review of the existing literature on head and neck manifestations of eosinophilic granulomatosis with polyangiitis to guide clinical decision making for the otolaryngologist.
Basnyat, Shristi, Goldfarb, Jared M., Nyquist, Gurston G., Rabinowitz, Mindy R., Rosen, Marc R.   +4 more
core   +1 more source