Results 1 to 10 of about 10,053 (177)

Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia [PDF]

Respirology Case Reports, 2023
We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study.
Hiroatsu Hatsukawa, Masaaki Ishikawa, Tomoyuki Hirai, Kazuo Endo, Emiko Saito, Hirotaka Matsumoto, Kouya Okazaki   +6 more
doaj   +4 more sources

Eosinophilic chronic rhinosinusitis

Allergology International, 2019
Eosinophilic chronic rhinosinusitis (ECRS) is a subgroup of chronic rhinosinusitis with nasal polyps (CRSwNP), which is associated with severe eosinophilic infiltration and intractable.
Shigeharu Fujieda, Yoshimasa Imoto, Yukinori Kato, Takahiro Ninomiya, Takahiro Tokunaga, Toshiki Tsutsumiuchi, Kanano Yoshida, Masanori Kidoguchi, Tetsuji Takabayashi   +8 more
doaj   +3 more sources

Lung function impairment and eosinophilia in patients with eosinophilic chronic rhinosinusitis [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: Eosinophilic chronic rhinosinusitis (ECRS) is characterized by intense eosinophil infiltration in nasal polyps (NPs), related to asthma comorbidity and elevated circulating eosinophil levels.
Yuki Sonoda, MD, Yoshimasa Imoto, MD, PhD, Ayako Maegawa, MD, Anna Shimizu, MD, Masanori Kidoguchi, MD, PhD, Rikako Gozawa, MD, Keisuke Koyama, MD, Naoto Adachi, MD, Taiyo Morikawa, MD, PhD, Yuto Miyazaki, MD, Takahiro Tokunaga, MD, PhD, Masafumi Sakashita, MD, PhD, Shigeharu Ueki, MD, PhD, Takechiyo Yamada, MD, PhD, Shigeharu Fujieda, MD, PhD   +14 more
doaj   +2 more sources

Eosinophilic Chronic Rhinosinusitis in Japan

Allergology International, 2010
: Chronic rhinosinusitis is a heterogeneous disease. In Europe and the United States, it has recently been divided into two subgroups: chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRSsNP).
Junichi Ishitoya, Yasunori Sakuma, Mamoru Tsukuda   +2 more
doaj   +3 more sources

Quantitative Real Time Polymerase Chain Reaction for measurement of human Interleukin – 5 receptor alpha spliced isoforms mRNA [PDF]

BMC Biotechnology, 2003
Background Expression of human Interleukin-5 receptor alpha (hIL-5Rα) is controlled by alternative splicing, which generates two different transcripts encoding a membrane-anchored and a soluble form of the receptor, respectively.
Gevaert Philippe, Speleman Frank, Holtappels Gabriele, Vandenbroucke Ina, Vandesompele Jo, Pérez Claudina, Van cauwenberge Paul, Bachert Claus   +7 more
doaj   +3 more sources

Eosinophilic Chronic Rhinosinusitis and Pathogenic Role of Protease. [PDF]

Int J Mol Sci, 2023
Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinus mucosa, and eosinophilic CRS (eCRS) is a subtype characterized by significant eosinophil infiltration and immune response by T-helper-2 cells. The pathogenesis of eCRS is heterogeneous and involves various environmental and host factors.
Kim J, Kwak S, Lee J, Park IH, Lee SH, Shin JM, Kim TH.   +6 more
europepmc   +3 more sources

Which are the best murine models to study Eosinophilic Chronic Rhinosinusitis? A contemporary review [PDF]

Brazilian Journal of Otorhinolaryngology, 2023
Objective: Mechanisms that lead to Eosinophilic Chronic Rhinosinusitis (ECRS) are not fully established in the literature. It is desirable to assess ECRS in a model that embraces most of the related events.
Francisco Leite-Santos, Edwin Tamashiro, Adriana de Andrade Batista Murashima, Wilma T. Anselmo-Lima, Fabiana C.P. Valera   +4 more
doaj   +2 more sources

Immunopathologic Role of Eosinophils in Eosinophilic Chronic Rhinosinusitis. [PDF]

Int J Mol Sci, 2022
Chronic rhinosinusitis (CRS) is a diverse chronic inflammatory disease of the sinonasal mucosa. CRS manifests itself in a variety of clinical and immunologic patterns. The histological hallmark of eosinophilic CRS (ECRS) is eosinophil infiltration. ECRS is associated with severe disease severity, increased comorbidity, and a higher recurrence rate, as ...
Shin SH, Ye MK, Park J, Geum SY.
europepmc   +3 more sources

Is the measurement of ethmoid sinus dominance in eosinophilic chronic rhinosinusitis accurate? [PDF]

Brazilian Journal of Otorhinolaryngology
Objective: An ethmoid-dominant shadow on computed tomography is an indicator of type 2 inflammation, and is one of the main items used to diagnose and classify the severity of eosinophilic chronic rhinosinusitis in the Japanese diagnostic criteria ...
Kosuke Akiyama, Yasushi Samukawa, Hiroshi Hoshikawa   +2 more
doaj   +2 more sources

Dupilumab improves eosinophilic otitis media associated with eosinophilic chronic rhinosinusitis

Allergology International, 2023
Background: Eosinophilic otitis media (EOM) is a refractory condition associated with eosinophilic chronic rhinosinusitis and bronchial asthma. EOM is characterized by type-2 inflammation and is refractory to various treatments.
Daiki Nakashima, Tsuguhisa Nakayama, Syunsuke Minagawa, Tetsuya Adachi, Chieko Mitsuyama, Yoko Shida, Tsuneya Nakajima, Shin-ichi Haruna, Yoshinori Matsuwaki   +8 more
doaj   +3 more sources