Results 11 to 20 of about 10,072 (196)

Alterations of gut microbiome in eosinophilic chronic rhinosinusitis. [PDF]

Eur Arch Otorhinolaryngol
A growing body of evidence has elucidated that the gut microbiota has a crucial impact on the pathophysiological process of atopic diseases. Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is a local atopic disease of the systemic immune response.
Liang Y, Zhang C, Xiong X, Mao X, Sun P, Yue Z, Wang W, Xie R, Zhang G.   +8 more
europepmc   +3 more sources

An eosinophil peroxidase activity assay accurately predicts eosinophilic chronic rhinosinusitis. [PDF]

J Allergy Clin Immunol, 2023
A definitive diagnosis of eosinophilic chronic rhinosinusitis (eCRS) requires invasive surgical tissue sampling and histologic enumeration of intact eosinophils. Eosinophil peroxidase (EPX) is an accurate biomarker of sinonasal tissue eosinophilia in CRS regardless of polyp status.
Smith KA, Gill AS, Pollard CE, Sumsion JS, Saffari H, Ashby S, Witt BL, Shipman PA, Gabrielsen DA, Yim MT, Levy JM, Oakley GM, Orlandi RR, Gleich GJ, Alt JA, Pulsipher A.   +15 more
europepmc   +3 more sources

Clinical Utility of Machine Learning Methods Using Regression Models for Diagnosing Eosinophilic Chronic Rhinosinusitis [PDF]

OTO Open
Objective Machine learning methods using regression models can predict actual values of histological eosinophil count from blood eosinophil levels. Therefore, these methods might be useful for diagnosing eosinophilic chronic rhinosinusitis, but their ...
Hiroatsu Hatsukawa, Masaaki Ishikawa
doaj   +2 more sources

In office sampling of eosinophil peroxidase to diagnose eosinophilic chronic rhinosinusitis. [PDF]

Int Forum Allergy Rhinol
AbstractBackgroundPractical biomarkers for endotypic characterization of chronic rhinosinusitis (CRS) remain elusive, hindering clinical utility. Eosinophil peroxidase (EPX) is an enzyme released by activated eosinophils. The objective of this study was to evaluate a clinic EPX assay as a marker of eosinophilic CRS.MethodsSubjects with and without CRS ...
Callander JK, Charbit AR, Khanna K, Fahy JV, Tang M, Liegeois M, Pletcher SD, Goldberg AN, Gurrola JG, Murr AH, Butrymowicz A, Loftus PA.   +11 more
europepmc   +5 more sources

Predictive modeling for eosinophilic chronic rhinosinusitis: Nomogram and four machine learning approaches [PDF]

iScience
Summary: Eosinophilic chronic rhinosinusitis (ECRS) is a distinct subset of chronic rhinosinusitis characterized by heightened eosinophilic infiltration and increased symptom severity, often resisting standard treatments.
Panhui Xiong, Junliang Chen, Yue Zhang, Longlan Shu, Yang Shen, Yue Gu, Yijun Liu, Dayu Guan, Bowen Zheng, Yucheng Yang   +9 more
doaj   +2 more sources

Analysis of the Construction of a Predictive Model for Eosinophilic Chronic Rhinosinusitis [PDF]

Journal of Asthma and Allergy
Shuo Wu,1,2 Jiahong Lao,1 Feitong Jian1 1E.N.T. Department, the 3rd Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2School of Biomedical Engineering, Sun Yat-Sen University, Shenzhen, People’s Republic of ...
Wu S, Lao J, Jian F
doaj   +2 more sources

Assessing chronic rhinosinusitis with nasal polyps severity by “Japanese epidemiological survey of refractory eosinophilic chronic rhinosinusitis” algorithm [PDF]

Exploration of Asthma & Allergy, 2023
Aim: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex disease with different subtypes that affect patients’ quality of life. This study aim to evaluate the severity of CRSwNP and the risk of treatment resistance using the “Japanese ...
Sérgio Duarte Dortas Jr, Bianca Victoria de Oliveira Martins, Fabiana Chagas da Cruz, Kelielson Cardoso de Macêdo Cruz, Elaine Silva Oliveira, José Elabras Filho, Priscila Novaes Ferraiolo, Solange Oliveira Rodrigues Valle   +7 more
doaj   +1 more source

Endotyping of nasal polyps in a multiracial Asian population [PDF]

Rhinology Online, 2022
Background: Chronic rhinosinusitis is a heterogenous disease with variation in the endotypes of nasal polyps, with type 2 inflammation being more prevalent in Caucasian populations whereas Chinese populations are more heterogenous. We aim to describe the
Shuhui Xu, M. Vallei, Jacqueline Hwang Siok Gek, Charn Tze Choong, Neville Wei Yang Teo   +4 more
doaj   +1 more source

Interferon-α action in cytokine profile in eosinophilic nasal polyp cultures

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: Chronic rhinosinusitis is currently classified into two types: chronic rhinosinusitis without nasal polyps and chronic rhinosinusitis with nasal polyps.
Júlio Cláudio Sousa, Renata Margarida Etchbehere, Eduardo Arthur Rodovalho Alves, Letícia Montes Stark, Eddie Fernando Cândido Murta, Márcia Antoniazi Michelin   +5 more
doaj   +1 more source

Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis [PDF]

International Journal of Medical Arts, 2021
Background: Chronic rhinosinusitis associated with nasal polypi [CRSwNP] is one of the two major chronic rhinosinusitis phenotypes. The histopathological changes of such condition may differ between primary and chronic types.Aim of the work: To ...
Wael Fawzy Ismaiel, Ahmed Abd Alrahman Ibrahim, Sami Abdullah Mohammed   +2 more
doaj   +1 more source