Results 31 to 40 of about 10,072 (196)

LTD4 and TGF-β1 induce the expression of metalloproteinase-1 in chronic rhinosinusitis via a cysteinyl leukotriene receptor 1-related mechanism [PDF]

, 2016
A
Bachert, Claus, Claeys, Cindy, Holtappels, Gabriële, Perez Novo, Claudina, Pezato, Rogerio   +4 more
core   +2 more sources

Omalizumab Restores Response to Corticosteroids in Patients with Eosinophilic Chronic Rhinosinusitis and Severe Asthma

Biomedicines, 2021
Eosinophilic chronic rhinosinusitis (ECRS), which is a subgroup of chronic rhinosinusitis with nasal polyps, is characterized by eosinophilic airway inflammation extending across both the upper and lower airways.
Yoshiki Kobayashi, Akira Kanda, Dan Van Bui, Yasutaka Yun, Linh Manh Nguyen, Hanh Hong Chu, Akitoshi Mitani, Kensuke Suzuki, Mikiya Asako, Hiroshi Iwai   +9 more
doaj   +1 more source

Recovery of smell sense loss by mepolizumab in a patient allergic to dermatophagoides and affected by chronic rhinosinusitis with nasal polyps [PDF]

, 2019
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently presents with dysfunction or loss of the sense of smell, resulting in a signifcant impairment in quality of life.
Cavaliere, Carlo, Ciotti, Mario, de Vincentiis, Marco, Frati, Franco, Greco, Antonio, Incorvaia, Cristoforo, Masieri, Simonetta, Messineo, Daniela   +7 more
core   +1 more source

Twelve-year follow-up study after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis [PDF]

, 2019
Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a therapeutic challenge because of the high recurrence rate. Surgical intervention should be considered in patients who fail to improve after medical treatment.
Bachert, Claus, Bosteels, Cedric, CALUS, LIEN, Dejonckheere, Sarah, Gevaert, Philippe, Holtappels, Gabriële, VAN BRUAENE, NICHOLAS, Van Zele, Thibaut   +7 more
core   +1 more source

The changes of clinical and histological characteristics of chronic rhinosinusitis in 18 years: Was there an inflammatory pattern shift in southern China?

World Allergy Organization Journal, 2021
Background: Nowadays, the heterogeneity of chronic rhinosinusitis (CRS) has attracted extensive attention. The histological patterns and clinical characteristics may vary greatly in different areas and among different groups of people.
Xin Luo, Zhaofeng Xu, Kejun Zuo, Jie Deng, Wenxiang Gao, Lijie Jiang, Lei Xu, Zhaoqi Huang, Jianbo Shi, Yinyan Lai   +9 more
doaj   +1 more source

Predictors of the enhanced response to mepolizumab treatment for severe eosinophilic asthma: A retrospective, long-term study

Cogent Medicine, 2020
Mepolizumab significantly reduces the number of annual exacerbations (AEs) and the maintenance dose of systemic corticosteroids (CSs) in patients with severe eosinophilic asthma (SEA).
Takanori Numata, Hanae Miyagawa, Hironori Kawamoto, Masahiro Yoshida, Hirofumi Utsumi, Mitsuo Hashimoto, Shunsuke Minagawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano   +9 more
doaj   +1 more source

Treatments of refractory eosinophilic lung diseases with biologics

Allergology International, 2023
Biologics targeting the molecules associated with type 2 inflammation have significantly improved the outcomes of patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP).
Koichiro Asano, Yuzo Suzuki, Jun Tanaka, Konomi Kobayashi, Yosuke Kamide   +4 more
doaj   +1 more source

Topical and systemic antifungal therapy for chronic rhinosinusitis [PDF]

, 2018
Background: This review adds to a series of reviews looking at primary medical management options for patients with chronic rhinosinusitis.  Chronic rhinosinusitis is common and characterised by inflammation of the lining of the nose and paranasal ...
Balk, Bent, Braun, Chakrabarti, Chan, Chen, Cho, Chong, Chong, Chong, Corradini, Deka, DeMarcantonio, Drunen, Ebbens, Ebbens, Ebbens, Ebbens, Ebbens, Ebbens, Egger, Erskine, Fokkens, Fokkens, Frigas, Gerlinger, Gerlinger, Gliklich, Gupta, Hashemi, Hastan, Head, Head, Head, Helbling, Hofman, Hopkins, Jiang, Jiang, Joshi, Juniper, Kennedy, Kern, Keswani, Khalil, Lackner, Larsen, Liang, Lopatin, Mistry, Nikakhlagh, Panda, Patro, Philpott, Ponikau, Ponikau, Ragab, Ragab, Ravikumar, Ricchetti, Ricchetti, Rojita, Sacks, Sherris, Shin, Sok, Somu, Tan, Thamboo, Tomassen, Verma, Weschta, Weschta, Wild, Yousefi, Zhang, Zhang, Zhang   +77 more
core   +1 more source

Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. [PDF]

, 2017
The recent discovery of group 2 innate lymphoid cells (ILC2s) has caused a paradigm shift in the understanding of allergic airway disease pathogenesis.
Cavagnero, Kellen, Doherty, Taylor A
core   +2 more sources

The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma

Allergy, Asthma & Clinical Immunology, 2011
This case reports the unique association of eosinophilic gastrointestinal disease with eosinophilic bronchitis, asthma and chronic rhinosinusitis and some features of lymphocytic hypereosinophilic syndrome, describes a diagnostic protocol for patients ...
Nair Parameswaran, Ochkur Sergei I, Protheroe Cheryl, Simms Elizabeth, Lee Nancy A, Lee James J   +5 more
doaj   +1 more source