Results 51 to 60 of about 5,939 (161)

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

A fatal eosinophilic granulomatosis with polyangiitis case presenting intracerebral hemorrhage and thrombocytopenia

Journal of Allergy and Clinical Immunology: Global, 2023
We report the case of a patient with eosinophilic granulomatosis with polyangiitis and unexplained thrombocytopenia that culminated in a fatal intracerebral hemorrhage.
Quan Hong Nguyen, PhD, MD, Hang Thi - Thuy Tran, MS, MD, Tuyen Manh Nguyen, MS, MD, Ngoc Hoang Nguyen, PhD, MD   +3 more
doaj   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Eosinophilic granulomatosis with polyangiitis

, 2019
26 years ...
Vincent Cottin, Kais Ahmad, Mouhamad Nasser, Claudia Valenzuela, Matthieu Groh, Benjamin Terrier, Julie Traclet   +6 more
  +4 more sources

Aspergillosis myocarditis in the immunocompromised host

IDCases, 2019
Invasive cardiac aspergillosis has been rarely described in immunocompromised patients. This disease is difficult to diagnose by conventional laboratory, microbiologic, and imaging techniques, and is often recognized only post-mortem. The authors present
Sean S. Bullis, Alison Krywanczyk, Andrew J. Hale   +2 more
doaj   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

ANCA-associated vasculitis in childhood: recent advances

Italian Journal of Pediatrics, 2017
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener’s), microscopic polyangiitis (MPA) and eosinophilic ...
Marta Calatroni, Elena Oliva, Davide Gianfreda, Gina Gregorini, Marco Allinovi, Giuseppe A. Ramirez, Enrica P. Bozzolo, Sara Monti, Claudia Bracaglia, Giulia Marucci, Monica Bodria, Renato A. Sinico, Federico Pieruzzi, Gabriella Moroni, Serena Pastore, Giacomo Emmi, Pasquale Esposito, Mariagrazia Catanoso, Giancarlo Barbano, Alice Bonanni, Augusto Vaglio   +20 more
doaj   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

Allergy, EarlyView.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S. Bleier, Marco Caminati, Diego M. Conti, Eugenio De Corso, Mina Gaga, Valerie J. Lund, Corrado Pelaia, Anju T. Peters, Glenis K. Scadding, Martin Wagenmann, Riyad O. Al‐Lehebi, Guy G. Brusselle, Philippe Gevaert, Liam G. Heaney, Stella E. Lee, Florence Schleich, Frederik Trinkmann, Peter W. Hellings, Wytske J. Fokkens, Paola Rogliani   +22 more
wiley   +1 more source

Psoriasis‐like skin rash triggered by a local infection in a patient with eosinophilic granulomatosis with polyangiitis that was well controlled by mepolizumab treatment

Clinical Case Reports, 2023
Key Clinical message A patient with eosinophilic granulomatosis with polyangiitis, who was well‐controlled by pharmacotherapy, developed a psoriasis‐like rash due to a local infection. It represents the consequence of an immunologic imbalance. Abstract A
Naho Yokota, Makoto Kondo, Akinobu Hayashi, Masako Ichishi, Yoshiaki Matsushima, Takehisa Nakanishi, Koji Habe, Keiichi Yamanaka   +7 more
doaj   +1 more source