Results 61 to 70 of about 9,401 (207)

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

Eosinophilic bronchitis, eosinophilic granuloma, and eosinophilic bronchopneumopathy in 75 dogs (2006-2016). [PDF]

, 2019
BackgroundEosinophilic lung disease is a poorly understood inflammatory airway disease that results in substantial morbidity.ObjectiveTo describe clinical findings in dogs with eosinophilic lung disease defined on the basis of radiographic, bronchoscopic,
Dear, Jonathan D, Hulsebosch, Sean E, Johnson, Eric G, Johnson, Lynelle R, Vernau, William   +4 more
core   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Potential masking of new-onset or relapsed eosinophilic granulomatosis with polyangiitis during benralizumab treatment: A case series

Journal of Allergy and Clinical Immunology: Global
Eosinophilic granulomatosis with polyangiitis can manifest without eosinophilia and eosinophilic infiltration during benralizumab treatment, emphasizing the need for clinical vigilance beyond eosinophil counts.
Shin-ichiro Ohmura, MD, PhD, Haruka Yonezawa, MD, Yusuke Ohkubo, MD   +2 more
doaj   +1 more source

Benralizumab for eosinophilic granulomatosis with polyangiitis

Annals of the Rheumatic Diseases, 2023
Benralizumab is effective in the treatment of eosinophilic asthma and is being investigated for the treatment of other eosinophil-associated diseases. Reports on the use of benralizumab for the treatment of eosinophilic granulomatosis with polyangiitis (EGPA) are limited to case reports and small case series.We conducted a multicentre, retrospective ...
Cottu, Adrien, Groh, Matthieu, Desaintjean, Charlene, Marchand-Adam, Sylvain, Guillevin, Loïc, Puechal, Xavier, Beaumesnil, Stacy, Lazaro, Estibaliz, Samson, Maxime, Taille, Camille, Durel, Cécile-Audrey, Diot, Elizabeth, Nicolas, Sarah, Guilleminault, Laurent, Ebbo, Mikael, Cathebras, Pascal, Dupin, Clairelyne, Yildiz, Halil, Belfeki, Nabil, Pugnet, Grégory, Chauvin, Pierre, Jouneau, Stephane, Lifermann, Francois, Martellosio, Jean-Philippe, Cottin, Vincent, Terrier, Benjamin, French Vasculitis Study Group   +26 more
openaire   +3 more sources

Idiopathic Eosinophilic Pneumonia with Associated Pulmonary Vasculitis in Horse: A Case Series [PDF]

, 2016
Various eosinophilic lesions and their association with diseases have been described in horses. Multisystemic Eosinophilic Epitheliotropic Disease (MEED) characterized by eosinophilic granulomas in various organs represent the most diffuse manifestation.
Francesca Mariotti, Giacomo Rossi, Gian Enrico Magi, null null, null null, null null, null null, Subeide Mari   +7 more
core   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Differential diagnosis of granulomatous lung disease: clues and pitfalls

European Respiratory Review, 2017
Granulomatous lung diseases are a heterogeneous group of disorders that have a wide spectrum of pathologies with variable clinical manifestations and outcomes.
Shinichiro Ohshimo, Josune Guzman, Ulrich Costabel, Francesco Bonella   +3 more
doaj   +1 more source

Prediction of Relapse and Glucocorticoid Dependence in Eosinophilic Granulomatosis With Polyangiitis: Findings From a Large European Cohort

Arthritis &Rheumatology, EarlyView.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterized by eosinophilia, asthma, and ear, nose, and throat (ENT) involvement. Although glucocorticoids (GCs) are effective in controlling symptoms, relapses and GC dependence are common. The aim of this study was to develop predictive models for vasculitis
Matthias Papo, Pauline Martinot, Renato A. Sinico, Vítor Silvestre‐Teixeira, Nils Venhoff, Maria‐Letizia Urban, Michele Iudici, Juliane Mahrhold, Francesco Locatelli, Giulia Cassone, Franco Schiavon, Benjamin Seeliger, Thomas Neumann, Claudia Feder, Matthieu Groh, Chiara Marvisi, Maxime Samson, Thomas Barba, David Jayne, Arianna Troilo, Jens Thiel, Bernhard Hellmich, Sara Monti, Carlomaurizio Montecucco, Carlo Salvarani, Jean‐Emmanuel Kahn, Bernard Bonnotte, Cécile‐Audrey Durel, Xavier Puéchal, Luc Mouthon, Loïc Guillevin, Giacomo Emmi, Augusto Vaglio, Raphaël Porcher, Benjamin Terrier, on behalf of the French Vasculitis Study Group and the Eosinophilic Granulomatosis with Polyangiitis European Study Group   +35 more
wiley   +1 more source

Flare of eosinophilic granulomatosis with polyangiitis related to pregnancy: Case report and review of the literature

Respiratory Medicine Case Reports, 2019
Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by excessive eosinophil accumulation in the peripheral blood and affected tissues with development of granulomatous vasculitic organ damage.
Osamu Matsuno, Seijiro Minamoto
doaj   +1 more source