Results 71 to 80 of about 64,509,941 (193)

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Granulomatosis with polyangiitis – therapeutic challenge

, 2016
The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small- to medium-sized blood vessels.
Małgorzata Wisłowska, Dorota Szydlarska   +1 more
core   +1 more source

COVID-19 and eosinophilic granulomatosis with polyangiitis or COVID-19 mimicking eosinophilic granulomatosis with polyangiitis?

, 2021
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Coronavirus disease 2019 (COVID-19) and eosinophilic granulomatosis with polyangiitis (EGPA) share similarities in clinical, imaging findings and may ...
Omma, Ahmet, KÜÇÜKŞAHİN, ORHAN, Güven, Serdar Can, Erden, ABDULSAMET, Akdag, Ahmet Gokhan, Özdemir, Bahar, Apaydin, Hakan, Ates, İhsan, Karakas, Özlem, Armagan, Berkan   +9 more
core   +1 more source

A fatal eosinophilic granulomatosis with polyangiitis case presenting intracerebral hemorrhage and thrombocytopenia

Journal of Allergy and Clinical Immunology: Global, 2023
We report the case of a patient with eosinophilic granulomatosis with polyangiitis and unexplained thrombocytopenia that culminated in a fatal intracerebral hemorrhage.
Quan Hong Nguyen, PhD, MD, Hang Thi - Thuy Tran, MS, MD, Tuyen Manh Nguyen, MS, MD, Ngoc Hoang Nguyen, PhD, MD   +3 more
doaj   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European multicenter observational study [PDF]

, 2021
Mepolizumab proved efficacious for eosinophilic granulomatosis with polyangiitis (EGPA, former Churg-Strauss) at the dosage of 300mg/4 weeks in the randomized controlled MIRRA trial.
Lombardi, Carlo, Jayne, David, Chiara Baldini, Maxime Samson, Vincent Cottin, Crimi, Claudia, Moroni, Luca, Anna Luise Kernder, European EGPA Study Group, Jan Schroeder, Padoan, Roberto, Claudia Crimi, Dagna, Lorenzo, Filippo Fagni, Egan, Allyson, Giacomo Emmi, Franceschini, Franco, Schiavon, Franco, Federico Alberici, Angelo Vacca, Florenzo Iannone, Mouhamad Nasser, David Jayne, Allyson Egan, Urban, Maria Letizia, Nasser, Mouhamad, Berti, Alvise, Federica Bello, Paola Toniati, Fraticelli, Paolo, Domenico Prisco, Fagni, Filippo, Baldini, Chiara, Moosig, Frank, Carlo Salvarani, Mohammad, Aladdin J., Franco Schiavon, Monti, Sara, Mohammad, Aladdin J, Luca Moroni, Neumann, Thomas, Simone Negrini, Giuseppe Lopalco, Carlo Lombardi, Schroeder, Jan, Pavel Novikov, Bernhard Hellmich, Davide Firinu, Ribi, Camillo, Georgina Espígol-Frigolé, Cohen Tervaert, Jan Willem, Cottin, Vincent, Lunardi, Claudio, Kernder, Anna Luise, Chiara Marvisi, Sinico, Renato Alberto, Roccatello, Dario, Frank Moosig, Renato Alberto Sinico, Samson, Maxime, Parronchi, Paola, Marco Folci, Salvarani, Carlo, Novikov, Pavel, Espígol-Frigolé, Georgina, Maria Letizia Urban, Bettiol, Alessandra, Toniati, Paola, Thomas Neumann, Ramirez, Giuseppe Alvise, Firinu, Davide, Paolo Fraticelli, Vaglio, Augusto, Silvagni, Ettore, Prisco, Domenico, Fiori, Davide, Marvisi, Chiara, Iannone, Florenzo, Jan Willem Cohen Tervaert, Quartuccio, Luca, Ettore Silvagni, Franco Franceschini, Benjamin Seeliger, Cinetto, Francesco, Aladdin J. Mohammad, Emmi, Giacomo, Roberto Padoan, Giuseppe Alvise Ramirez, Espígol‐Frigolé, Georgina, Paola Parronchi, Lorenzo Dagna, Vacca, Angelo, Luca Quartuccio, Georgina Espígol‐Frigolé, Francesco Cinetto, Sara Monti, Stefano Del Giacco, Negrini, Simone, Alessandra Bettiol, Dario Roccatello, Hellmich, Bernhard, Seeliger, Benjamin, Bargagli, Elena, Davide Fiori, Bello, Federica, Augusto Vaglio, Lopalco, Giuseppe, Aladdin J Mohammad, Del Giacco, Stefano, Folci, Marco, Elena Bargagli, Alberici, Federico, Camillo Ribi, Alvise Berti, Claudio Lunardi   +114 more
core   +4 more sources

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 986-995, September 2026.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

A variety of clinical presentations of eosinophilic granulomatosis with polyangiitis: a comprehensive review

Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by eosinophilic granulomatous vasculitis. Typical symptoms include late-onset bronchial asthma and blood and tissue eosinophilia.
Agata Sebastian, Joanna Kosałka-Węgiel
core   +1 more source

Aspergillosis myocarditis in the immunocompromised host

IDCases, 2019
Invasive cardiac aspergillosis has been rarely described in immunocompromised patients. This disease is difficult to diagnose by conventional laboratory, microbiologic, and imaging techniques, and is often recognized only post-mortem. The authors present
Sean S. Bullis, Alison Krywanczyk, Andrew J. Hale   +2 more
doaj   +1 more source

Assessing Surgical Extent Before Biologic Therapy for CRSwNP

International Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 1043-1045, September 2026.
Key Points Nearly two‐thirds of patients had no surgery or incomplete sinus surgery before biologics. Among all sinuses, the frontal sinus was the least frequently addressed before biologics.
Alison J. Yu, Kristina A. LaPointe, Kaitlyn Ann Roberts, Michelle Yu, James N. Palmer, Alan D. Workman, Jose L. Mattos, Rodney J. Schlosser, Zachary M. Soler   +8 more
wiley   +1 more source