Results 81 to 90 of about 64,509,941 (193)

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, Volume 81, Issue 9, Page 3171-3184, September 2026.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Eosinophilic granulomatosis with polyangiitis and laryngeal involvement: Review of the literature and a cross-sectional prospective experience

, 2018
Background Eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis show variable otorhinolaryngological involvement. Up to 14 per cent of granulomatosis with polyangiitis patients have subglottis involvement; little is known ...
Bartoli, M. L., C Baldini, S Fortunato, P L Paggiaro, Fortunato, S., M L Bartoli, Sellari-Franceschini, S., Cristofani-Mencacci, L., S Sellari-Franceschini, Baldini, C., I Dallan, Seccia, V., M Latorre, L Cristofani-Mencacci, Paggiaro, P. L., V Seccia, Latorre, M., Dallan, I.   +17 more
core   +1 more source

ANCA-associated vasculitis in childhood: recent advances

Italian Journal of Pediatrics, 2017
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener’s), microscopic polyangiitis (MPA) and eosinophilic ...
Marta Calatroni, Elena Oliva, Davide Gianfreda, Gina Gregorini, Marco Allinovi, Giuseppe A. Ramirez, Enrica P. Bozzolo, Sara Monti, Claudia Bracaglia, Giulia Marucci, Monica Bodria, Renato A. Sinico, Federico Pieruzzi, Gabriella Moroni, Serena Pastore, Giacomo Emmi, Pasquale Esposito, Mariagrazia Catanoso, Giancarlo Barbano, Alice Bonanni, Augusto Vaglio   +20 more
doaj   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

Allergy, Volume 81, Issue 9, Page 3146-3156, September 2026.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S. Bleier, Marco Caminati, Diego M. Conti, Eugenio De Corso, Mina Gaga, Valerie J. Lund, Corrado Pelaia, Anju T. Peters, Glenis K. Scadding, Martin Wagenmann, Riyad O. Al‐Lehebi, Guy G. Brusselle, Philippe Gevaert, Liam G. Heaney, Stella E. Lee, Florence Schleich, Frederik Trinkmann, Peter W. Hellings, Wytske J. Fokkens, Paola Rogliani   +22 more
wiley   +1 more source

Eosinophilic granulomatosis with polyangiitis induced by montelukast

Acta clinica Croatica
Leukotriene receptor antagonists are a class of drugs used in maintenance therapy of asthma. Among the adverse effects induced by them, particularly by montelukast, is eosinophilic granulomatosis with polyangiitis (EGPA), which manifests as a form of vasculitis co-occurring with severe asthma and eosinophilia.
Grama, Paul, Ureche, Corina, Zah, Corina Adelina, Buzoianu, Anca Dana, Bocsan, Ioana Corina   +4 more
openaire   +3 more sources

Oral corticosteroid-sparing effects of reslizumab in the treatment of eosinophilic granulomatosis with polyangiitis

, 2020
Blockade of interleukin-5 with reslizumab appears to have significant oral corticosteroid sparing effects in patients with eosinophilic granulomatosis with polyangiitis and severe eosinophilic asthma http://bit.ly/2D2yYSK.
Kent, Brian D, Green, Linda, Kavanagh, Joanne, Nanzer, Alexandra M, Fernandes, Mariana, Jackson, David J, d'Ancona, Grainne, Thomson, Louise, Agarwal, Sangita, Roxas, Cris   +9 more
core   +1 more source

Tubulointerstitial Nephritis With Uveitis (TINU) Syndrome: A Case Series and Review of Literature

Nephrology, Volume 31, Issue 9, September 2026.
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) syndrome is a rare disorder characterised by the simultaneous or sequential occurrence of acute tubulointerstitial nephritis and uveitis, in the absence of systemic disease. Its true prevalence is likely underestimated, as renal and ocular manifestations may not appear concurrently. We conducted
Weaam Ali, Nidhi Agrawal, Smeeta Sinha, Dimitrios Poulikakos, Jamil Choudhury, Constantina Chrysochou   +5 more
wiley   +1 more source

Significance of PR3-ANCA positivity in eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

, 2021
Only a third of patients with eosinophilic granulomatosis with polyangiitis (EGPA) are ANCA-positive, mainly directed against MPO. ANCA directed against PR3 are rarely found in EGPA.
Matthias Papo, Jayne, David, Maxime Samson, Thomas Neumann, Matthieu Groh, Vaglio, Augusto, Guillevin, Loïc, Claus Kroegel, Marvisi, Chiara, Xavier Puéchal, Thomas Barba, Carlomaurizio Montecucco, Giacomo Emmi, Sinico, Renato A, Schiavon, Franco, Jens Thiel, David Jayne, French Vasculitis Study Group and the EGPA European Study Group, Michele Iudici, Mahrhold, Juliane, Juliane Mahrhold, Benjamin Seeliger, Barba, Thomas, Jean-Emmanuel Kahn, Nils Venhoff, Durel, Cécile-Audrey, Kahn, Jean-Emmanuel, Emmi, Giacomo, Terrier, Benjamin, Benjamin Terrier, Groh, Matthieu, Carlo Salvarani, Mouthon, Luc, Franco Schiavon, Monti, Sara, Arianna Troilo, Venhoff, Nils, Urban, Maria-Letizia, Iudici, Michele, Maria-Letizia Urban, Sara Monti, Neumann, Thomas, Vítor Teixeira, Cassone, Giulia, Troilo, Arianna, Hellmich, Bernhard, Seeliger, Benjamin, Kroegel, Claus, Bernhard Hellmich, Cécile-Audrey Durel, Montecucco, Carlomaurizio, Bonnotte, Bernard, Luc Mouthon, Chiara Marvisi, Locatelli, Francesco, Renato A Sinico, Giulia Cassone, Teixeira, Vítor, Augusto Vaglio, Papo, Matthias, French Vasculitis Study Group, the EGPA European Study Group, Thiel, Jens, Bernard Bonnotte, Loïc Guillevin, Francesco Locatelli, Samson, Maxime, Puéchal, Xavier, Salvarani, Carlo   +68 more
core   +1 more source

Rituximab for the treatment of eosinophilic granulomatosis with polyangiitis (Churg-Strauss).

, 2016
Conventional treatment of eosinophilic granulomatosis with polyangiitis (EGPA) (Churg-Strauss) with glucocorticoids, with or without additional immunosuppressive drugs, is limited by partial efficacy, frequent toxicity and a high relapse rate.
Hot, A, Moosig, F, Jayne, D R W, Merkel, P A, Smith, R, Guerry, M-J, Guillevin, L, Sivasothy, P, Amudala, N, Arndt, F, Lund University., Mohammad, Aladdin, Mohammad, Aladdin,   +12 more
core   +1 more source

Retention of a Patency Capsule Shell in a Nonsteroidal Anti‐Inflammatory Drug‐Induced Small‐Bowel Stricture, Detected and Retrieved by Balloon‐Assisted Enteroscopy: Emphasizing the Importance of Confirming Capsule Excretion

Journal of Digestive Diseases, EarlyView.
Shinichiro Kawatoko, Tomohiro Nagasue, Akihiro Shigemori, Akihiro Yoshida, Junji Umeno   +4 more
wiley   +1 more source