Results 171 to 180 of about 212,373 (377)

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Accepted Article.
Objectives Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The Phase III MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E Wechsler, Jared Silver, Gerhard Wolff, Robert G Price, Rejina Verghis, Peter F Weller, Peter A Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

Environmental exposure of the general population to cadmium as a risk factor of the damage to the nervous system: A critical review of current data

Journal of Applied Toxicology, Volume 43, Issue 1, Page 66-88, January 2023., 2023
Abstract Nowadays, more and more attention has been focused on the risk of the neurotoxic action of cadmium (Cd) under environmental exposure. Due to the growing incidence of nervous system diseases, including neurodegenerative changes, and suggested involvement of Cd in their aetiopathogenesis, this review aimed to discuss critically this element ...
Agnieszka Ruczaj, Małgorzata M. Brzóska   +1 more
wiley   +1 more source

Osteopontin mediated eosinophils activation by group II innate lymphoid cells

World Allergy Organization Journal, 2022
Background: Osteopontin (OPN) can regulate Th2 inflammation in allergic rhinitis (AR). A recent study suggested that group II innate lymphoid cells (ILC2s) were very important for airway inflammation.
Qingxiang Zeng, PhD, Luo Xi, PhD, Yinhui Zeng, MD, Wenlong Liu, PhD, Lifeng Zhou, MD   +4 more
doaj  

Expanding Training Data for Endoscopic Phenotyping of Eosinophilic Esophagitis [PDF]

arXiv
Eosinophilic esophagitis (EoE) is a chronic esophageal disorder marked by eosinophil-dominated inflammation. Diagnosing EoE usually involves endoscopic inspection of the esophageal mucosa and obtaining esophageal biopsies for histologic confirmation.
arxiv  

MOTION PICTURE STUDIES ON DEGRANULATION OF HORSE EOSINOPHILS DURING PHAGOCYTOSIS [PDF]

, 1963
G. T. L. Archer, James G. Hirsch
openalex   +1 more source

Fighting Antibiotic Resistance: Insights Into Human Barriers and New Opportunities

BioEssays, EarlyView.
Antibiotic resistance is a public health issue leading to the emergence of multi‐resistant bacteria. Human‐dependent factors are now driving the increase of resistance, notably through antibiotic misuse in human and animal health and environmental pollution.
Aubin Pitiot, Camille Rolin, Carole Seguin‐Devaux, Jacques Zimmer   +3 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Phagocytosis by Human Eosinophils [PDF]

, 1968
Martin J. Cline, Jon M. Hanifin, Robert I. Lehrer   +2 more
openalex   +1 more source

Diffusion and Multi-Domain Adaptation Methods for Eosinophil Segmentation [PDF]

arXiv
Eosinophilic Esophagitis (EoE) represents a challenging condition for medical providers today. The cause is currently unknown, the impact on a patient's daily life is significant, and it is increasing in prevalence. Traditional approaches for medical image diagnosis such as standard deep learning algorithms are limited by the relatively small amount of
arxiv  

Blood and sputum biomarkers in COPD and asthma: a review [PDF]

, 2016
Chronic obstructive pulmonary disease (COPD) and asthma are lung inflammatory diseases that represent major public health problems. The primary, and often unique, method to evaluate lung function is spirometry, which reflects disease severity rather than
Conti, V, De Marchis, L, Graziani, C, Ialleni, E, Leone, V, Munafò, G, Paone, G, Ramaccia, M, Salducci, M   +8 more
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