Results 11 to 20 of about 223 (65)
Identification of linear B cell epitopes on the E146L protein of African swine fever virus with monoclonal antibodies [PDF]
Virology JournalThe outbreak and spread of African swine fever virus (ASFV) have caused considerable economic losses to the pig industry worldwide. Currently, to promote the development of effective ASF vaccines, especially subunit vaccines, more antigenic protein ...
Shu-Jian Zhang +4 more
doaj +2 more sources
Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence and virulence from attenuated BeninΔDP148R [PDF]
, 2021 AbstractThe limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress towards vaccine development. In this study we investigated the effect of deleting combinations of different genes from a previously attenuated virus, BeninΔDP148R on: virus replication in macrophages, virus ...
Vlad Petrovan +7 more
openaire +1 more source
Deletion Mutants of the Attenuated Recombinant ASF Virus, BA71ΔCD2, Show Decreased Vaccine Efficacy
Viruses, 2021 African swine fever (ASF) has become the major threat to the global swine industry. Lack of available commercial vaccines complicates the implementation of global control strategies. So far, only live attenuated ASF viruses (ASFV) have demonstrated solid
Elisabeth Lopez +15 more
doaj +1 more source
The African swine fever virus lectin EP153R modulates the surface membrane expression of MHC class I antigens [PDF]
Archives of Virology, 2010 We have modeled a 3D structure for the C-type lectin domain of the African swine fever virus protein EP153R, based on the structure of CD69, CD94 and Ly49A cell receptors, and this model predicts that a dimer of EP153R may establish an asymmetric interaction with one MHC-I molecule.
Hurtado, Carolina +8 more
openaire +3 more sources
Pathogens, 2022 African swine fever (ASF) was first introduced into Northern China in 2018 and has spread through China since then. Here, we extracted the viral DNA from the blood samples from an ASF outbreak farm in Guangdong province, China and sequenced the whole ...
Xun Wang +6 more
doaj +1 more source
Production of Recombinant African Swine Fever Viruses: Speeding Up the Process
Viruses, 2020 African swine fever (ASF) is a devastating disease in pigs, with no vaccines for control. The genetic manipulation of African swine fever virus (ASFV) is often tedious and time consuming.
Anusyah Rathakrishnan +3 more
doaj +1 more source
Virology, 2000 The open reading frame EP153R, located within the EcoRI E' fragment of the African swine fever (ASF) virus genome, is predicted to encode a membrane protein of 153 amino acids that presents significant homology to the N-terminal region of several CD44 molecules.
Galindo, Immaculada +4 more
openaire +3 more sources
Virology, 2004 The open reading frame EP153R of African swine fever virus (ASFV) encodes a nonessential protein that has been involved in the hemadsorption process induced in virus-infected cells. By the use of a virus deletion mutant lacking the EP153R gene, we have detected, in several virus-sensitive cells, increased levels of caspase-3 and cell death as compared ...
Hurtado, Carolina +8 more
openaire +3 more sources
Viruses, 2017 African swine fever virus (ASFV) is a large DNA virus that replicates predominantly in the cell cytoplasm and is the only member of the Asfarviridae family.
Linda K. Dixon +3 more
doaj +1 more source
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.The African swine fever virus (ASFV) causes African swine fever (ASF), a highly lethal disease affecting domestic pigs and wild boars. Since its initial outbreak in October 2019 in Yeoncheon, Gyeonggi Province, ASF has continued to spread in South Korea.
Garam Kim +5 more
wiley +1 more source