Results 21 to 30 of about 223 (65)

Virus-like and Virus Replicon Particles Targeting Multiple B-Cell Antigens Do Not Protect Against African Swine Fever Virus

Vaccines
Background: African swine fever virus (ASFV) causes a fatal hemorrhagic disease in domestic pigs and wild boars. While live attenuated vaccines (LAVs) provide protection, their use raises safety concerns.
Kirill Lotonin, Obdulio García-Nicolás, Normann Kilb, Stefan Krämer, Xinyue Chang, Paul Engeroff, Kemal Mehinagic, Noelle Donzé, Francisco Brito, Matthias Liniger, Ilva Lieknina, Darja Cernova, Ieva Balta, Gabriela González-García, Paloma Rueda, Gert Zimmer, Charaf Benarafa, Nicolas Ruggli, Günter Roth, Kaspars Tars, Martin Bachmann, Artur Summerfield   +21 more
doaj   +1 more source

A dual-gene-deleted ASFV Lv17/WB/Rie1-ΔCD candidate administered orally to wild boar confers DIVA-compatible protection against virulent challenge

Veterinary Quarterly
African swine fever (ASF) continues to expand worldwide. Recent detection in wild boar in Spain highlights the urgent need for effective control tools, with oral vaccination as a key priority.
Jose A. Barasona, Aleksandra Kosowska, Gabriela González-García, Marta Díaz-Frutos, Giulia Franzoni, Paola Nicolussi, Nestor Porras, Mónica Sánchez-Segovia, Daniel De Antonio-Gómez, Paloma Rueda, Sandra Barroso-Arévalo   +10 more
doaj   +1 more source

Modulation of MHC class I expression by African swine fever virus and the role of virus proteins EP153R and CD2v

, 2014
Various DNA viruses, including pox- and herpesviruses, express proteins which down-regulate host MHC class I antigen expression as an immune evasion strategy. Previous studies into whether ASFV modulates expression of the porcine MHC class I molecule, SLA I, have not provided a clear answer. In this thesis, the effect of African swine fever virus (ASFV)
openaire   +3 more sources

Characterization of three African swine fever viruses from different clinical settings revealed a potential attenuation mechanism

Animal Diseases
African swine fever (ASF) is an acute and fatal hemorrhagic disease in domestic pigs and wild boars caused by African swine fever virus (ASFV) that currently threatens the pig industry worldwide. Since the 2018 ASF outbreak in China, ASFV has evolved and
Jiajia Zhang, Yuening Wang, Kaili Zhang, Dafu Deng, Kai Peng, Wanglong Zheng, Nanhua Chen, Penggang Liu, Shaobin Shang, Ruichao Li, Jianzhong Zhu   +10 more
doaj   +1 more source

Modulation of MHC class I expression by African swine fever virus and the role of virus proteins EP153R and CD2v

, 2016
Various DNA viruses, including pox- and herpesviruses, express proteins which downregulate host MHC class I antigen expression as an immune evasion strategy. Previous studies into whether ASFV modulates expression of the porcine MHC class I molecule, SLA-I, have not provided a clear answer. In this thesis, the effect of African swine fever virus (ASFV)
openaire   +1 more source

Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus. [PDF]

J Virol, 2023
Pérez-Núñez D, García-Belmonte R, Riera E, Fernández-Sesma MH, Vigara-Astillero G, Revilla Y.   +5 more
europepmc   +1 more source

A Whole-Genome Analysis of the African Swine Fever Virus That Circulated during the First Outbreak in Vietnam in 2019 and Subsequently in 2022. [PDF]

Viruses, 2023
Le VP, Ahn MJ, Kim JS, Jung MC, Yoon SW, Trinh TBN, Le TN, Kim HK, Kang JA, Lim JW, Yeom M, Na W, Xie X, Feng Z, Song D, Jeong DG.   +15 more
europepmc   +1 more source

Vaccines for African swine fever: an update. [PDF]

Front Microbiol, 2023
Zhang H, Zhao S, Zhang H, Qin Z, Shan H, Cai X.   +5 more
europepmc   +1 more source

Subtle Genetic Shifts of African Swine Fever Virus Among Vietnamese Domestic Swine Following Live-Attenuated Vaccine Commercialization. [PDF]

Transbound Emerg Dis
Nguyen TC, Tantitaveewattana P, Pamornchainavakul N, Do DT, Kedkovid R, Thanawongnuwech R.   +5 more
europepmc   +1 more source

Autophagy regulation and viral exploitation: insights into African swine fever virus pathogenesis. [PDF]

Front Cell Infect Microbiol
Li R, Liu X, Lei Y, Bao J, Zhang Z, Chen X.   +5 more
europepmc   +1 more source