Results 231 to 240 of about 712,631 (292)

Membrane-Associated Biomolecules for Synthetic Cell Signalling. [PDF]

Chembiochem
Dack C, Li B, Newell C, Booth MJ.
europepmc   +1 more source

HMGB1 impairs nasal epithelial barrier via regulating autophagy in the pathogenesis of allergic rhinitis. [PDF]

World Allergy Organ J
Fan Y, Xu M, Ren L, Lu C, Li Y, Chen F, Ma Z, Li Y, Cao X, Li J.   +9 more
europepmc   +1 more source

Lymphocyte activation gene 3 in autoimmune disease: from molecular mechanisms to clinical applications. [PDF]

Front Immunol
Guo L, Pan L, Liu C, Yang S.
europepmc   +1 more source

Gut microbiota-atrium axis: Microbiota metabolite-mediated regulation of the NLRP3 inflammasome in atrial fibrillation-pathophysiological roles and therapeutic perspectives. [PDF]

Heart Rhythm O2
Ling X, Hu J.
europepmc   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Targeting the COX-2/PGE₂ axis to enhance NK and T cell immunotherapy in brain tumors. [PDF]

Cancer Immunol Immunother
Shen CJ, Florentino-Krasnov J, Liao YC, Tang HW, Nainggolan BWM, Chiang YH, Hsu TI.   +6 more
europepmc   +1 more source

Synergistic Integration of LiCF3SO3 in PVdF‐HFP/PVAc Polymer Blends: Multifaceted Analysis From Microstructure to Electrochemical Properties

Journal of Applied Polymer Science, EarlyView.
Solid polymer electrolyte films of PVdF‐HFP/PVAc blend with LiCF3SO3 were prepared by solution casting. XRD, FESEM, and FTIR confirmed reduced crystallinity and enhanced amorphous nature. Ionic conductivity reached 3.46 × 10−4 S cm−1 for optimized SP4.
B. Praveen Kumar, P. Ajay Kumar, P. Missak Swarup Raju   +2 more
wiley   +1 more source

Novel Compounds as TREM2 Agonists for Treating Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Nasu-Hakola Disease, and Stroke. [PDF]

ACS Med Chem Lett
Sabnis RW, Sabnis AR.
europepmc   +1 more source

Clinical efficacy and putative analgesic mechanism of heat-sensitive moxibustion for chronic nonspecific low back pain: a single-arm before-after study based on the brain-gut-immune axis. [PDF]

Front Integr Neurosci
Xie Y, Li C.
europepmc   +1 more source