Epicutaneous immunotherapy for food allergy: a systematic review and meta-analysis [PDF]
Systematic Reviews, 2023 Background There is ongoing debate about the safety and efficacy of epicutaneous immunotherapy (EPIT) in treating food allergies. The systematic review and meta-analysis aimed to evaluate the safety and efficacy of EPIT.
Xiaohong Xiang +8 more
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Innovative delivery systems for epicutaneous immunotherapy [PDF]
Frontiers in Immunology, 2023 Allergen-specific immunotherapy (AIT) describes the establishment of peripheral tolerance through repeated allergen exposure, which qualifies as the only curative treatment for allergic diseases.
Zhen Wang, Lingzhi Wu, Wei Wang
doaj +4 more sources
Innovative Systems to Deliver Allergen Powder for Epicutaneous Immunotherapy [PDF]
Frontiers in Immunology, 2021 Allergy is a disorder owing to hyperimmune responses to a particular kind of substance like food and the disease remains a serious healthcare burden worldwide.
Yensheng Wang, Yifei Kong, Mei X. Wu
doaj +5 more sources
Recent advances in epicutaneous immunotherapy and potential applications in food allergy [PDF]
Frontiers in Allergy, 2023 Given the potent immunological properties of the skin, epicutaneous immunotherapy (EPIT) emerges as a promising treatment approach for inducing immune tolerance, particularly for food allergies.
Pierre-Louis Hervé +6 more
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Treatment of Intestinal Inflammation With Epicutaneous Immunotherapy Requires TGF-β and IL-10 but Not Foxp3+ Tregs [PDF]
Frontiers in Immunology, 2021 Background: Inflammatory bowel disease (IBD) involves an increase in T effector cells in the intestines that disrupts the normal balance with T regulatory cells (Tregs). A therapy that restores this balance has the potential to treat IBD.
Xin Chen +5 more
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The Role of Regulatory T Cells in Epicutaneous Immunotherapy for Food Allergy [PDF]
Frontiers in Immunology, 2021 In recent decades, a rapid increase in the prevalence of food allergies has led to extensive research on novel treatment strategies and their mechanisms.
Guirong Liu +4 more
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The safety and efficacy of oral immunotherapy compared to epicutaneous immunotherapy in peanut allergen desensitisation amongst the paediatric cohort—a narrative review [PDF]
Frontiers in AllergyPeanut allergies result from a type 1 hypersensitivity reaction, with a prevalence of approximately 1% in children under 5 years of age. The allergens that instigate this reaction are the peanut proteins (Ara h 1–Ara h 8) for which IgE antibodies are ...
Ehtesam A. Chowdhury, Olivia C. Jadeja
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Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice [PDF]
Clinical and Translational Allergy, 2012 Background Epicutaneous immunotherapy (EPIT) on intact skin with an epicutaneous delivery system has already been used in preclinical and clinical studies.
Mondoulet Lucie +7 more
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Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies. [PDF]
Eur J ImmunolMurine allergy model outcomes differ by sensitization route, allergen type, and mouse strain, influencing mechanisms such as IgE and mast cell involvement and the therapeutic relevance of each model. Understanding how experimental parameters shape outcomes is essential for selecting appropriate models and effectively translating findings to clinical ...
Nagata Y, Suzuki R.
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Epicutaneous immunotherapy in rhino-conjunctivitis and food allergies: a review of the literature [PDF]
Journal of Translational Medicine, 2018 Background Epicutaneous immunotherapy (EPIT) is a new way of allergen administration that has a high rate of adherence and safety. The aim of this manuscript is to review clinical trials on EPIT for respiratory and food allergies published in the last 10
Susanna Esposito +7 more
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