Epicutaneous immunotherapy for food allergy: a systematic review and meta-analysis [PDF]
Systematic Reviews, 2023 Background There is ongoing debate about the safety and efficacy of epicutaneous immunotherapy (EPIT) in treating food allergies. The systematic review and meta-analysis aimed to evaluate the safety and efficacy of EPIT.
Xiaohong Xiang +8 more
doaj +10 more sources
Innovative delivery systems for epicutaneous immunotherapy [PDF]
Frontiers in Immunology, 2023 Allergen-specific immunotherapy (AIT) describes the establishment of peripheral tolerance through repeated allergen exposure, which qualifies as the only curative treatment for allergic diseases.
Zhen Wang, Lingzhi Wu, Wei Wang
doaj +5 more sources
Innovative Systems to Deliver Allergen Powder for Epicutaneous Immunotherapy [PDF]
Frontiers in Immunology, 2021 Allergy is a disorder owing to hyperimmune responses to a particular kind of substance like food and the disease remains a serious healthcare burden worldwide.
Yensheng Wang, Yifei Kong, Mei X. Wu
doaj +6 more sources
Recent advances in epicutaneous immunotherapy and potential applications in food allergy [PDF]
Frontiers in Allergy, 2023 Given the potent immunological properties of the skin, epicutaneous immunotherapy (EPIT) emerges as a promising treatment approach for inducing immune tolerance, particularly for food allergies.
Pierre-Louis Hervé +6 more
doaj +5 more sources
Mechanisms of desensitization with oral immunotherapy and epicutaneous immunotherapy. [PDF]
J Food Allergy, 2023 Background: Oral immunotherapy (OIT) and epicutaneous immunotherapy (EPIT) are emerging therapies for food allergy. With several recently published exploratory trials and randomized controlled clinical trials that support these procedures, there is a ...
Bellanti JA.
europepmc +4 more sources
Epicutaneous immunotherapy for the treatment of peanut allergy. [PDF]
AllergyPeanut allergy treatment options remain limited, but novel approaches are being studied, including epicutaneous immunotherapy (EPIT). EPIT uses the cutaneous immune system to promote tolerance to food allergens.
Ravindran M +5 more
europepmc +4 more sources
Epicutaneous Immunotherapy with CBir1 Alleviates Intestinal Inflammation. [PDF]
Inflamm Bowel Dis, 2023 BACKGROUND Inflammatory bowel disease may be due to failed tolerance to normal gut bacteria. We demonstrate that epicutaneous immunotherapy (ET) to ovalbumin can alleviate colitis in murine models.
Chen X, Elson CO, Dunkin D.
europepmc +4 more sources
The safety and efficacy of oral immunotherapy compared to epicutaneous immunotherapy in peanut allergen desensitisation amongst the paediatric cohort—a narrative review [PDF]
Frontiers in AllergyPeanut allergies result from a type 1 hypersensitivity reaction, with a prevalence of approximately 1% in children under 5 years of age. The allergens that instigate this reaction are the peanut proteins (Ara h 1–Ara h 8) for which IgE antibodies are ...
Ehtesam A. Chowdhury, Olivia C. Jadeja
doaj +3 more sources
Treatment of Intestinal Inflammation With Epicutaneous Immunotherapy Requires TGF-β and IL-10 but Not Foxp3+ Tregs [PDF]
Frontiers in Immunology, 2021 Background: Inflammatory bowel disease (IBD) involves an increase in T effector cells in the intestines that disrupts the normal balance with T regulatory cells (Tregs). A therapy that restores this balance has the potential to treat IBD.
Xin Chen +5 more
doaj +3 more sources
The Role of Regulatory T Cells in Epicutaneous Immunotherapy for Food Allergy [PDF]
Frontiers in Immunology, 2021 In recent decades, a rapid increase in the prevalence of food allergies has led to extensive research on novel treatment strategies and their mechanisms.
Guirong Liu +4 more
doaj +3 more sources