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Epicutaneous Immunotherapy in Grass-Induced Allergic Rhinitis
Current Allergy and Asthma Reports, 2010As we approach the 100th anniversary of the first use of subcutaneous immunotherapy, a robust literature has demonstrated its efficacy in the treatment of allergic rhinitis and asthma, its ability to provide lasting efficacy following discontinuation, as well as its ability to potentially deter the allergic march. Despite these positive findings, it is
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Epicutaneous immunotherapy: A review of safety and efficacy
Pediatric Allergy and ImmunologyAbstractEpcutaneous immunotherapy (EPIT) is a novel, non‐oral route of allergen immunotherapy, utilizing the skin and its robust density of epidermal Langerhans cells (LC) for antigen presentation. This space is non‐vascularized and impermeable, which limits allergen exposure into the bloodstream but preserves antigen presentation to regional lymph ...
Aikaterini Anagnostou, Matthew Greenhawt
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Advances in the management of peanut allergy (oral immunotherapy and epicutaneous immunotherapy)
Allergy and Asthma Proceedings, 2020Background: Peanut allergy affects up to 2% of the general population and carries not only the risk of potentially life-threatening allergic reactions but also negatively impacts day to day life for patients and their families. Advances in knowledge in immunotherapy is providing families with options for proactive treatment. Objective: To examine the
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Safety and efficacy of epicutaneous immunotherapy for food allergy
Pediatric Allergy and Immunology, 2018AbstractFood allergy is increasingly common in children, affecting about 4%‐8%. The mainstays of management remain allergen avoidance and emergency preparedness to treat allergic reactions with emergency medications. Unfortunately, these approaches are unsatisfactory for many patients and their families as the restrictions, constant vigilance, and ...
Julie Wang, Hugh A. Sampson
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Epigenetic Changes Following Epicutaneous Immunotherapy in Peanut Sensitized Mice
Journal of Allergy and Clinical Immunology, 2015Results: In splenocytes, a significant hypermethylation in GATA-3 CpG islands was induced by EPIT versus Sham, starting from the 4 of treatment ...
Mondoulet, Lucie +7 more
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Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy
Journal of Allergy and Clinical Immunology, 2009Subcutaneous allergen-specific immunotherapy is an effective treatment of IgE-mediated allergies, but it requires repeated allergen injections with a risk of systemic allergic reactions. Transcutaneous immunotherapy may improve patient compliance and safety.To assess the safety and efficacy of epicutaneous allergen immunotherapy.This monocentric ...
Senti, G +7 more
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Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology, 2021
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Engineered Iontophoresis Patch for Epicutaneous Allergen‐specific Immunotherapy
Advanced Functional MaterialsAbstractEpidermal immunotherapy represents an emerging treatment method for allergic diseases. Nevertheless, an unformidable obstacle for epidermal drug delivery is the dense stratum corneum of the skin. Here, iontophoresis technology is utilized for epidermal delivery of allergen protein.
Zhiting Cao +7 more
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Treatment of Colitis by Epicutaneous Immunotherapy in a Murine Model
2015Treatment of Colitis by Epicutaneous Immunotherapy in a Murine Model.
Dunkin, David +8 more
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